Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Journal ArticleDOI
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
TL;DR: This review focuses on various potential applications of supramolecular hydrogels as molecular biomaterials, classified by their applications in cell cultures, tissue engineering, cell behavior, imaging, and unique applications of hydrogelators.
Journal ArticleDOI
Biomedical Applications of Supramolecular Systems Based on Host-Guest Interactions.
Xing Ma,Yanli Zhao +1 more
TL;DR: Host−Guest Supramolecular Chemistry A 1.1.1: Aims to explore the role of “ghostly” particles in the determination of chiral stationary phases and their role in the “spatially modified” states.
Journal ArticleDOI
Hydrogels in a historical perspective: from simple networks to smart materials.
Sytze J. Buwalda,Kristel W. M. Boere,Pieter J. Dijkstra,Jan Feijen,Tina Vermonden,Wim E. Hennink +5 more
TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Christopher B. Rodell,Sean P. Arlauckas,Michael F. Cuccarese,Christopher Garris,Ran Li,Maaz S. Ahmed,Rainer H. Kohler,Mikael J. Pittet,Ralph Weissleder +8 more
TL;DR: The ability of rationally engineered drug–nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy is demonstrated and R848, an agonist of the toll-like receptors TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro.
References
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Book ChapterDOI
Cyclodextrin-based molecular machines
TL;DR: Attempts to design and synthesize molecular-level machines using cyclodextrins as a cyclic component of molecular shuttles, motors, and machines are described.
Journal ArticleDOI
Complex formation between poly(ethylene glycol) and α-cyclodextrin
Akira Harada,Mikiharu Kamachi +1 more
TL;DR: La cyclodextrine α forme avec des PEG de masses moleculaires variables des complexes cristallins stables jusqu'a 300°C dans lesquels 2 motifs ethylene oxyde sont lies a une cavite de la cyclodextrine α.
Journal ArticleDOI
Cyclodextrin-based supramolecular polymers
TL;DR: This tutorial review overviews construction of some supramolecular architectures formed by cyclodextrins or their derivatives with guest molecules.
Journal ArticleDOI
Cyclodextrin-based supramolecular architectures: Syntheses, structures, and applications for drug and gene delivery
Jun Li,Xian Jun Loh +1 more
TL;DR: New cationic polyrotaxanes composed of multiple oligoethylenimine-grafted CDs threaded and end-capped on a block copolymer chain were designed and synthesized as a new class of polymeric gene delivery vectors, where the chain-interlocked cationIC cyclic units formed an integrated supramolecular entity to function as a macromolecular gene vector.
Journal ArticleDOI
Macroscopic self-assembly through molecular recognition
TL;DR: It is demonstrated that well-defined molecular-recognition events can be used to direct the assembly of macroscopic objects into larger aggregated structures.