Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Luminescence Imaging of Acute Liver Injury by Biodegradable and Biocompatible Nanoprobes.
Hui Tao,Hui Tao,Jia Wei Guo,Yongchang Ma,Yang Zhao,Taotao Jin,Lijuan Gu,Yin Dou,Jinyi Liu,Houyuan Hu,Xiaoxing Xiong,Jianxiang Zhang +11 more
TL;DR: LaCD NP can be further developed as an effective and biocompatible luminescent nanoprobe for in vivo dynamic detection of the development of neutrophil-mediated acute liver injury and is also promising for diagnosis of other neutrophils-associated liver diseases.
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Mechanical microencapsulation: The best technique in taste masking for the manufacturing scale - Effect of polymer encapsulation on drug targeting
TL;DR: A scoring system was established to evaluate each process using recent published data of selected factors suggesting that Mechanical microencapsulation along with complexation with cyclodextrin suggest that these methods are the most preferable for drug taste masking.
Journal ArticleDOI
Cyclodextrin-based poly(pseudo)rotaxanes for transdermal delivery of carvedilol.
Stephânia Fleury Taveira,Angela Varela-Garcia,Bruno dos Santos Souza,Ricardo Neves Marreto,Manuel Martín-Pastor,Angel Concheiro,Carmen Alvarez-Lorenzo +6 more
TL;DR: The results evidenced the versatility of the formulations in terms of rheological behavior and drug release patterns, which can be adjusted for CAR transdermal delivery.
Journal IssueDOI
Cyclodextrin Complexes: An Approach to Improve the Physicochemical Properties of Drugs and Applications of Cyclodextrin Complexes
TL;DR: Cyclodextrins, because of their continuing ability to find several novel applications in drug delivery, are expected to solve many problems accompanied with the delivery of different novel drugs through various delivery routes.
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Magnetite nanoparticles modified β-cyclodextrin PolymerCoupled with KMnO4 oxidation for adsorption and degradation of acetaminophen.
TL;DR: The repeated degradation experiments demonstrated that MNPs/β-CDP had mechanic stability and reusability and provide novel ideas for the degradation of persistent contaminants in water environments.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.