Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Modulation of the cooperativity in the assembly of multistranded supramolecular polymers
TL;DR: The cooperativity factor α does not properly account for the cooperativity behaviour of multistranded polymers, or any supramolecular polymer with a nucleus composed of more than 2 building blocks, and a model that accounts for this responsiveness is developed by assuming the binding of the salt countercations to the double-stranded polymer.
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Entrapping Atomically Precise Clusters in Cyclodextrin-Functionalized Aminoclay Sheets: Synthesis and Enhanced Luminescence
TL;DR: In this paper, a unique covalently linked aminoclay substrate, grafted with β-cyclodextrin (AC-CD), was prepared to entrap luminescent silver nanoclusters.
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Controlled drug delivery mediated by cyclodextrin-based supramolecular self-assembled carriers: From design to clinical performances
Jana Ghitman,Stefan Ioan Voicu +1 more
TL;DR: In this article , the authors present the latest achievements in the field of nanoparticles-based supramolecular architectures, taken into account the main methods of synthesis and the stimuli that control the release.
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Theoretical study of an anti-Markovnikov addition reaction catalyzed by β-cyclodextrin
TL;DR: The calculated 1H nuclear magnetic resonance (1H NMR) spectrum of β-CD implied that the chemical shifts of its protons change and H3 and H5 move to higher fields upon complexation, while the calculated 13C nuclear magnetic Resonance spectrum of styrene suggested that this molecule is electrophilic.
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Fast Curing Multifunctional Tissue Adhesives of Sericin-Based Polyurethane-Acrylates for Sternal Closure
Sevgi Balcioğlu,Samir Abbas Ali Noma,Ahmet Ulu,Merve Goksin Karaaslan-Tunc,Onural Ozhan,Suleyman Koytepe,Hakan Parlakpinar,Nigar Vardi,Mehmet Cengiz Çolak,Burhan Ates +9 more
TL;DR: The results indicate that the adhesive may be suitable for sternal fixation by preventing the disadvantages of the steel wires and promoting tissue healing.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.