Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Drug-in-cyclodextrin-in-liposomes: a promising delivery system for hydrophobic drugs
TL;DR: The present article reviews the preparation, characterization and application of DCLs, especially as antitumor or transdermal carriers and seems to be a suitable targeted drug delivery system because they have a fast onset action with prolonged drug release process and the significantly enhanced drug-loading capacity.
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Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy
TL;DR: A strategy using supramolecular aggregation-induced emission (AIE) nanodots for image-guided drug delivery, which integrate both the advantages of AIE and supramolescular nanomaterials, which exhibit excellent tumor inhibition ability in both subcutaneous and orthotopic pancreatic tumor models.
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Cyclodextrins in capillary electrophoresis: Recent developments and new trends
Laura Escuder-Gilabert,Yolanda Martín-Biosca,M.J. Medina-Hernández,Salvador Sagrado,Salvador Sagrado +4 more
TL;DR: This review focuses the attention in the CD-CE topic over the January 2013-February 2014 period (not covered by previous more general CE-reviews), and trends and initiatives attending to real needs or practical criteria are outlined.
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Cyclodextrin-based supramolecular nanoparticles for biomedical applications
TL;DR: This review will focus on SNPs involving CD as the host entity, and the forces that induce the assembly between the different components and, therefore, result in the formation of stable and controllable nanoparticles.
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Guanidinocalix[5]arene for sensitive fluorescence detection and magnetic removal of perfluorinated pollutants.
Zhe Zheng,Huijuan Yu,Wen-Chao Geng,Xin-Yue Hu,Yu-Ying Wang,Zhihao Li,Yuefei Wang,Dong-Sheng Guo +7 more
TL;DR: A guanidinocalix[5]arene is developed that selectively binds perfluorinated alkyl substances and allows for fluorescence detection as well as removal of the pollutants in contaminated water.
References
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Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
Journal ArticleDOI
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.