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Open AccessJournal ArticleDOI

Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.

Jianxiang Zhang, +1 more
- 01 Aug 2013 - 
- Vol. 65, Iss: 9, pp 1215-1233
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.

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Citations
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Journal ArticleDOI

Prebiotic-like cyclodextrin assisted silybin on NAFLD through restoring liver and gut homeostasis.

TL;DR: Wang et al. as discussed by the authors developed a silybin-2-hydroxypropyl-β-cyclodextrin inclusion (SHβCD) to improve the therapeutic efficacy of SLN and elucidate the mechanisms of improvement.
Book ChapterDOI

Cyclodextrin-Based Carriers for Delivery of Dietary Phytochemicals

TL;DR: This work reviews the applications of natural and chemically modified cyclodextrins for the delivery of dietary phytochemicals and focuses mainly on outcomes of inclusion complexes for enhancing solubility, bioavailability and efficacy of the delivered phytochemistryicals.
Journal ArticleDOI

Interaction poses, intermolecular forces, dynamic preferences between flavonoids and maltosyl-β-cyclodextrin

TL;DR: In this article , the binding ability of eight flavonoids with four common CDs (α-, β-, methyl-β-, γ-CD) was investigated by using phase solubility, ultraviolet, infrared, X-ray diffraction, differential scanning calorimetry, molecular docking and ONIOM calculations.
References
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Journal ArticleDOI

Effect of pegylation on pharmaceuticals

TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
Journal ArticleDOI

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
Journal ArticleDOI

Acidification of the endocytic and exocytic pathways

TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.
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