Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
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Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
TL;DR: This review focuses on various potential applications of supramolecular hydrogels as molecular biomaterials, classified by their applications in cell cultures, tissue engineering, cell behavior, imaging, and unique applications of hydrogelators.
Journal ArticleDOI
Biomedical Applications of Supramolecular Systems Based on Host-Guest Interactions.
Xing Ma,Yanli Zhao +1 more
TL;DR: Host−Guest Supramolecular Chemistry A 1.1.1: Aims to explore the role of “ghostly” particles in the determination of chiral stationary phases and their role in the “spatially modified” states.
Journal ArticleDOI
Hydrogels in a historical perspective: from simple networks to smart materials.
Sytze J. Buwalda,Kristel W. M. Boere,Pieter J. Dijkstra,Jan Feijen,Tina Vermonden,Wim E. Hennink +5 more
TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Christopher B. Rodell,Sean P. Arlauckas,Michael F. Cuccarese,Christopher Garris,Ran Li,Maaz S. Ahmed,Rainer H. Kohler,Mikael J. Pittet,Ralph Weissleder +8 more
TL;DR: The ability of rationally engineered drug–nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy is demonstrated and R848, an agonist of the toll-like receptors TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro.
References
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Journal ArticleDOI
A cationic prodrug/therapeutic gene nanocomplex for the synergistic treatment of tumors
TL;DR: It was found that PC-Dox/wt p53 complexes promoted the inhibition of tumor growth in vivo and prolonged the survival time of tumor-bearing mice.
Book ChapterDOI
Polymerization of Included Monomers and Behaviour of Resulting Polymers
TL;DR: Eggersdorfer et al. as mentioned in this paper used a homologous series of water-soluble and chiral host molecules which can be used as models for studying weak interactions.
Journal ArticleDOI
Star Polymers with Both Temperature Sensitivity and Inclusion Functionalities
TL;DR: In this paper, the authors designed and synthesized novel star poly(N-isopropylacrylamide) (star-PNIPAm) and star NIPAm with cyclodextrin (CD) end groups by atom transfer radical polymerization (ATRP).
Journal ArticleDOI
Cyclodextrin liquid crystals: synthesis and self-organisation of amphiphilic thio-β-cyclodextrins
TL;DR: Heptakis(6-S-alkyl-6-thio)-cyclomaltoheptaoses (where alkyl is a C2, C4, C10, C16 and C18 unit) have been shown to form thermotropic liquid crystals as mentioned in this paper.
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Supramolecular dissociation of biodegradable polyrotaxanes by enzymatic terminal hydrolysis
Tooru Ooya,Nobuhiko Yui +1 more
TL;DR: The complete dissociation of the polyrotaxanes by hydrolysis is considered to be due to the loosely packed association, presumably related to the rod-like structure.