Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Journal ArticleDOI
A theoretical basis for the enhancement of Seebeck coefficients in supramolecular thermocells
TL;DR: Seebeck coefficients of supramolecular thermocells harnessing four kinds of cyclodextrins as host molecules were investigated in this paper, and theoretical analysis revealed that association enthalpy between t...
Journal ArticleDOI
A new strategy for the construction of β-cyclodextrin-based magnetic nanocarriers: a molecular docking technique
TL;DR: The molecular docking technique could provide a significant reference for the fast selection of an effective surface coating during the construction of high-performance β-CD-based magnetic nanocarriers.
Journal ArticleDOI
Reinforcement of ‘imine-hydroxyl chelation pocket’ by encapsulating into the β-CD cavity for the sterically protective detection of Al3+
Krishnamoorthy Sivakumar,G. Parinamachivayam,M. Murali Krishnan,V. Ragavendran,Thambusamy Stalin,K. Premkumar,Sujay Chakravarty,A. Bharathi +7 more
TL;DR: In this article, the effect of encapsulating a schiff base probe; o-phenolnaphthylimine (pni) into β-cyclodextrin (β-CD) and its impact on the detection of Al3+ was investigated using the spectrofluorometric technique.
Book ChapterDOI
Nanostructured organic-organic bio-hybrid delivery systems
Lígia Nunes de Morais Ribeiro,Ana C. S. Alcantara,Michelle Franz-Montan,Verônica Muniz Couto,Silvia V. G. Nista,Eneida de Paula +5 more
TL;DR: Smart ORG-HYB responds to stimuli (temperature and pH), increasing tissue specificity and/or discharging drugs in a controlled manner, to provide sustained release, adhesiveness, permeation enhancement, and drug targeting.
Journal ArticleDOI
Self-assembly of cyclic hexamers of γ-cyclodextrin in a metallosupramolecular framework with D-penicillamine
TL;DR: The first structurally characterized self-assembly of non-substituted γ-cyclodextrin molecules into cyclic hexamers is reported, which was realized in a chiral coordination framework composed of complex-anions with d-penicillamine rather than l- or dl-peniillamine.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
Journal ArticleDOI
Cyclodextrin Drug Carrier Systems.
Journal ArticleDOI
Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.