Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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A Multifunctional Nanotherapy for Targeted Treatment of Colon Cancer by Simultaneously Regulating Tumor Microenvironment.
Qixiong Zhang,Fuzhong Zhang,Shanshan Li,Renfeng Liu,Taotao Jin,Yin Dou,Zhenhua Zhou,Jianxiang Zhang +7 more
TL;DR: Anticancer nanotherapies derived from intrinsic anti-inflammatory nanocarriers are promising for targeted combination treatment of inflammation-associated tumors by simultaneously shaping pro-inflammatory microenvironment toward a relatively normal niche sensitive to chemotherapy.
Journal ArticleDOI
Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment
Amina Ben Mihoub,Ludivine Larue,Albert Moussaron,Zahraa Youssef,Ludovic Colombeau,Francis Baros,Céline Frochot,Régis Vanderesse,Samir Acherar +8 more
TL;DR: The in vitro or/and in vivo use of natural and derived CDs to improve antitumoral PDT efficiency in aqueous media is described, including incorporating CD–PS systems into hybrid nanoparticles (NPs) using up-converting or other types of NPs, and (3) CDs with fullerenes as PSs.
Journal ArticleDOI
Competitive host-guest interaction between β-cyclodextrin polymer and pyrene-labeled probes for fluorescence analyses.
Pei Liu,Shan Sun,Xiaochen Guo,Xiaohai Yang,Jin Huang,Kemin Wang,Qing Wang,Jianbo Liu,Leiliang He +8 more
TL;DR: A novel homogeneous fluorescence analysis based on a novel competitive host-guest interaction (CHGI) mechanism between β-cyclodextrin polymer and pyrene-labeled probe for biochemical assay holds promising potential for detecting a broad range of other types of aptamer-binding chemicals and biomolecules.
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Preparation, characterization, and pharmacokinetics study of capsaicin via hydroxypropyl-beta-cyclodextrin encapsulation
Yingying Zhao,Chaonan Sun,Feng Shi,Caleb Kesse Firempong,Jiangnan Yu,Ximing Xu,Weiming Zhang +6 more
TL;DR: CAP exhibited significant aqueous solubility and oral bioavailability, as well as minimal irritation effect after forming inclusion complex with HP-β-CD, which could provide an equally important alternative option for the clinical use of CAP.
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Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy.
TL;DR: This review aims to highlight the developments in porphyrin-based structural modifications, with a specific emphasis on the role of PDT in anticancer treatment and the design of PSs to achieve a synergistic effect on multiple targets.
References
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Effect of pegylation on pharmaceuticals
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TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.