Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Complexation of a cationic pyrene derivative with sulfobutylether substituted β-cyclodextrin: Towards a stimulus-responsive supramolecular material
TL;DR: In this article, the interaction of SBE7-β-cyclodextrin with a versatile cationic fluorescent probe, 1-pyrenemethyl amine (PMA), using ground-state absorption, steady-state emission, and time-resolved emission measurements was investigated.
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Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry.
TL;DR: The peculiarities of the first- and second-order mass spectra of cyclic oligosaccharides (natural, synthetic and their derivatives and modifications: cyclodextrins, cycloglucans, cyclofructan, cyclooligoglucosamines, etc.) are discussed in this minireview.
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Functionalization of Gold Nanostars with Cationic β-Cyclodextrin-Based Polymer for Drug Co-Loading and SERS Monitoring.
Orlando Donoso-González,Lucas Lodeiro,A. E. Aliaga,Miguel A. Laguna-Bercero,Soledad Bollo,Marcelo J. Kogan,Nicolás Yutronic,Rodrigo Sierpe +7 more
TL;DR: In this article, the authors used Cationic β-cyclodextrin-based polymer (CCD/P) to load phenylethylamine (PhEA) and piperine (PIP) and evaluated SERS-based applications of the products.
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Supramolecular poly(N-acryloylmorpholine)-b-poly(d,l-lactide) pseudo-block copolymer via host-guest interaction for drug delivery
TL;DR: In this article, a pseudo-block copolymer was prepared from β-cyclodextrin terminated poly(N-acryloylmorpholine) (β-CD-PNAM) and adamantine-terminated linear poly(D,L-lactide) (AD-PDLLA), through host-guest interaction between β-CD and AD groups.
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Studies on pH and temperature dependence of inclusion complexes of bisdemethoxycurcumin with β-cyclodextrin derivatives
TL;DR: In this paper, the effect of pH and temperature on the inclusion complexes of bisdemethoxycurcumin (BDMC) with sulfobutylether-β-cyclodextrin (SBE-β)-CD and methylated-β -cyclodesxtrin(M-β-) was investigated by phase solubility and fluorescence spectroscopy methods.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.