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Journal ArticleDOI

Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.

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TLDR
This first global assessment of country-level population prevalence of chronic HBV infection found a wide variation between countries and highlights the need for continued prevention and control strategies and the collection of reliable epidemiologic data using standardised methodology.
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This article is published in The Lancet.The article was published on 2015-10-17. It has received 2130 citations till now. The article focuses on the topics: HBsAg & Hepatitis B virus.

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STAT3 directly regulates NKp46 transcription in NK cells of HBeAg-negative CHB patients.

TL;DR: Findings indicate that STAT3 is an important positive regulator of NK cells, and provide a new mechanism of NK cell dysfunction in chronic hepatitis B virus infection.
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Clinical implication of serum Wisteria floribunda agglutinin positive Mac‐2‐binding protein level on hepatitis B e‐antigen loss or seroconversion in hepatitis B e‐antigen positive patients

TL;DR: To examine the impact of pretreatment Wisteria floribunda agglutinin positive Mac‐2‐binding protein (WFA+‐M2BP) level on hepatitis B e‐antigen loss or HBeAg seroconversion for patients with nucleoside/nucleotide analog (NUC) therapy naive H beAg positive chronic hepatitis B (CHB).
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Serum hepatitis B virus RNA is a predictor of HBeAg seroconversion and virological response with entecavir treatment in chronic hepatitis B patients.

TL;DR: Serum HBV RNA was an independent indicator for predicting HBeAg seroconversion and virological response and PVR during treatment and was more likely in CHB patients withHBV RNA levels below 4.12 log10 copies/mL before treatment.
Journal ArticleDOI

Prevalence of hepatitis B and hepatitis C infection from a population-based study in Southern India.

TL;DR: The prevalence of HBV was 1.63% and HCV was 0.30% in Tamil Nadu, India, with significant variation among districts, and three-fourths ofHBV/HCV infected people were males.
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Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients

TL;DR: TLR2-ligand conjugation of the prototype HBV-core SLP reduced cross-presentation efficiency of the SLP-contained epitope by both monocyte-derived and naturally occurring DC subsets, providing an import step forward in the design of a therapeuticSLP-based vaccine to cure chronic HBV.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more
- 10 Jan 2015 - 
TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
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