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Journal ArticleDOI

Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.

Aparna Schweitzer, +4 more
- 17 Oct 2015 - 
- Vol. 386, Iss: 10003, pp 1546-1555
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TLDR
This first global assessment of country-level population prevalence of chronic HBV infection found a wide variation between countries and highlights the need for continued prevention and control strategies and the collection of reliable epidemiologic data using standardised methodology.
About: 
This article is published in The Lancet.The article was published on 2015-10-17. It has received 2130 citations till now. The article focuses on the topics: HBsAg & Hepatitis B virus.

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Citations
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Journal ArticleDOI

Human apolipoprotein E promotes hepatitis B virus infection and production.

Luhua Qiao, +1 more
- 08 Aug 2019 - 
TL;DR: It is found that human apoE is also associated with HBV and is required for efficient HBV infection and production, and inhibitors interfering with apolipoprotein E biogenesis, secretion, and/or binding to receptors may serve as antivirals for elimination of chronicHBV infection.
Journal ArticleDOI

Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9.

Dmitry Kostyushev, +6 more
- 12 Feb 2019 - 
TL;DR: It is concluded that CRISPR/Cas9 is a highly effective tool to degrade ccc DNA and first demonstrate that inhibiting NHEJ impairs cccDNA degradation.
Journal ArticleDOI

Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction.

Yuta Tsukamoto, +17 more
- 21 May 2018 - 
TL;DR: Results demonstrate that rosmarinic acid inhibits HBV replication in HBV-infected cells by specifically targeting ε-Pol binding.
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Progress in vaccination towards hepatitis B control and elimination in the Region of the Americas

Alba Maria Ropero Alvarez, +6 more
- 17 Apr 2017 - 
TL;DR: The achievements of vaccination programs in the Americas suggest that the elimination of perinatal and early childhood HB transmission could be feasible in the short-term, and may have already achieved the 2020 WHO goal for HB control.
Journal Article

HIV and Hepatitis Testing: Global Progress, Challenges, and Future Directions.

Philippa Easterbrook, +3 more
- 01 Jan 2016 - 
TL;DR: Key challenges in the hepatitis testing response are summarized, including lack of simple, reliable, and low-cost diagnostic tests, laboratory capacity, and testing facilities; inadequate data to guide country specific hepatitis testing approaches and who to screen; stigmatization and social marginalization of those with or at risk of viral hepatitis.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

David Moher, +4 more
- 21 Jul 2009 - 
TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

David Moher, +4 more
- 21 Jul 2009 - 
TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

David Moher, +4 more
- 01 Jan 2010 - 
TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more
- 10 Jan 2015 - 
TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.
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