Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.

doi:10.1016/S0140-6736(15)61412-X

Journal ArticleDOI

Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013.

Aparna Schweitzer, +4 more

- 17 Oct 2015 -

The Lancet

- Vol. 386, Iss: 10003, pp 1546-1555

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TLDR

This first global assessment of country-level population prevalence of chronic HBV infection found a wide variation between countries and highlights the need for continued prevention and control strategies and the collection of reliable epidemiologic data using standardised methodology.

About:

This article is published in The Lancet.The article was published on 2015-10-17. It has received 2130 citations till now. The article focuses on the topics: HBsAg & Hepatitis B virus.

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Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription.

Debora Salerno, +12 more

- 26 Feb 2020 -

Gut

TL;DR: The ability of HBx to bind RNA to impact on the epigenetic control of both viral cccDNA and host genes is highlighted and provide a new key to understand the role of DLEU2 and EZH2 overexpression in HBV-related HCCs and HBx contribution to hepatocytes transformation.

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Salvatore Vaccarella, +5 more

TL;DR: A new Scientific Publication from the International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization (WHO), examines the global problem of social inequalities in cancer.

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Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.

Klaus Klumpp, +8 more

- 01 Feb 2018 -

Gastroenterology

TL;DR: NVR3-778 has high antiviral activity in mice with humanized livers and stable HBV infection, reducing levels of serum HBV DNA and HBV RNA.

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Hepatitis B/C in the countries of the EU/EEA: a systematic review of the prevalence among at-risk groups.

Abby Falla, +5 more

- 12 Feb 2018 -

BMC Infectious Diseases

TL;DR: The findings of this study do not seem to strongly support the continued classification of MSM as a high risk group for chronic hepatitis B infection, however, they still consider MSM a key population for targeted action given the emerging evidence of viral hepatitis transmission within this risk group.

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Journal ArticleDOI

A potent human neutralizing antibody Fc-dependently reduces established HBV infections.

Dan Li, +13 more

- 26 Sep 2017 -

eLife

TL;DR: Novel human monoclonal antibodies are developed that block the engagement of preS1 with NTCP and neutralize HBV and HDV with high potency and suggest 2H5-A14 as a novel clinical candidate for HBV prevention and treatment of chronic HBV infection.

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References

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MSOR connections

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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

David Moher, +4 more

- 21 Jul 2009 -

Open Medicine

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.

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Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

David Moher, +4 more

- 01 Jan 2010 -

International Journal of Surgery

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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more

- 10 Jan 2015 -

The Lancet

TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.

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