Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition.
Pouya Saeedi,Inga Petersohn,Paraskevi Salpea,Belma Malanda,Suvi Karuranga,Nigel Unwin,Stephen Colagiuri,Leonor Guariguata,Ayesha A. Motala,Katherine Ogurtsova,Jonathan E. Shaw,Dominic Bright,Rhys Williams +12 more
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TLDR
Just under half a billion people are living with diabetes worldwide and the number is projected to increase by 25% in 2030 and 51% in 2045, with the prevalence higher in urban than rural areas, and in high-income than low-income countries.About:
This article is published in Diabetes Research and Clinical Practice.The article was published on 2019-09-10 and is currently open access. It has received 4865 citations till now.read more
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Design, Synthesis and Pharmacological Evaluation of Naphthofuran Derivatives as Potent SIRT1 Activators.
TL;DR: Based on the crystal structure of SIRT1, structure and ligand-based approaches were carried out, and a lead compound 4,456-0661 (renamed as M1) was identified as mentioned in this paper.
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Vitamin D protects against high glucose-induced pancreatic β-cell dysfunction via AMPK-NLRP3 inflammasome pathway
TL;DR: In this paper , a human cross-sectional study of 78 healthy, glucose-tolerant volunteers and 399 patients with type 2 diabetes was undertaken, and the relationship between serum 25(OH)D3 levels and β-cell function was assessed using Pearson correlation analysis and multiple linear regression, and a high-glucose diet-induced rat model of impaired glucose tolerance was used to evaluate the effects of cholecalciferol.
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A registry-based randomised trial comparing an SGLT2 inhibitor and metformin as standard treatment of early stage type 2 diabetes (SMARTEST): Rationale, design and protocol.
Johan Sundström,Robin Kristófi,Ollie Östlund,Louise Bennet,Björn Eliasson,Stefan Jansson,Janeth Leksell,Kristina E. Almby,Martin Lundqvist,Jan W. Eriksson +9 more
TL;DR: In this article, the authors compared the SGLT2 inhibitor dapagliflozin and metformin as first-line T2D medication with regard to development of complications in a registry-based randomised controlled trial.
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Clinical trials with plants in diabetes mellitus therapy: a systematic review.
TL;DR: The chronic metabolic disorder diabetes mellitus is a fast-growing global problem with huge social, health, and economic consequences, having one of the highest morbidities and mortality rates.
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Alzheimer's Disease and Type 2 Diabetes Mellitus: The Use of MCT Oil and a Ketogenic Diet.
Junpei Takeishi,Yasuko Tatewaki,Taizen Nakase,Yumi Takano,Naoki Tomita,Shuzo Yamamoto,Tatsushi Mutoh,Yasuyuki Taki +7 more
TL;DR: In this paper, medium-chain triglyceride (MCT) oil and a ketogenic diet were introduced as an alternative source of energy in the brain of Alzheimer's disease patients to promote ketone metabolism.
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Smith,Mari Smith,Badr Hasan Sobaih,Eugene Sobngwi,Reed J D Sorensen,Tatiane Cristina Moraes Sousa,Luciano A. Sposato,Chandrashekhar T Sreeramareddy,Vinay Srinivasan,Jeffrey D. Stanaway,Vasiliki Stathopoulou,Nicholas Steel,Murray B. Stein,Dan J. Stein,Dan J. Stein,Timothy J. Steiner,Timothy J. Steiner,Caitlyn Steiner,S. Steinke,S. Steinke,Mark A. Stokes,Lars Jacob Stovner,Bryan Strub,Michelle L Subart,Mu'awiyyah Babale Sufiyan,Bruno F. Sunguya,Bruno F. Sunguya,Patrick J Sur,Patrick J Sur,Soumya Swaminathan,Bryan L. Sykes,Dillon O Sylte,Rafael Tabarés-Seisdedos,Getachew Redae Taffere,Jukka Takala,Nikhil Tandon,Mohammad Tavakkoli,Nuno Taveira,Hugh R. Taylor,Arash Tehrani-Banihashemi,Tesfalidet Tekelab,Abdullah Sulieman Terkawi,Dawit Jember Tesfaye,Belay Tesssema,Ornwipa Thamsuwan,Katie E Thomas,Amanda G. Thrift,Tenaw Yimer Tiruye,Ruoyan Tobe-Gai,Mette Christophersen Tollånes,Mette Christophersen Tollånes,Marcello Tonelli,Roman Topor-Madry,Roman Topor-Madry,Miguel Tortajada,Mathilde Touvier,Bach Xuan Tran,Suryakant Tripathi,Christopher Troeger,Thomas Truelsen,Derrick Tsoi,Kald Beshir Tuem,Emin Murat Tuzcu,Stefanos Tyrovolas,Kingsley N. Ukwaja,Eduardo A. Undurraga,Eduardo A. Undurraga,Chigozie Jesse Uneke,Rachel L Updike,Olalekan A. Uthman,Benjamin S Chudi Uzochukwu,Job F M van Boven,Santosh Varughese,Tommi Vasankari,S Venkatesh,Narayanaswamy Venketasubramanian,Ramesh Vidavalur,Francesco Saverio Violante,Sergey K Vladimirov,Vasiliy Victorovich Vlassov,Stein Emil Vollset,Fiseha Wadilo,Tolassa Wakayo,Tolassa Wakayo,Yuan-Pang Wang,Marcia R. Weaver,Scott Weichenthal,Elisabete Weiderpass,Robert G. Weintraub,Andrea Werdecker,Ronny Westerman,Harvey Whiteford,Harvey Whiteford,Tissa Wijeratne,Charles Shey Wiysonge,Charles D.A. Wolfe,Charles D.A. Wolfe,Rachel Woodbrook,Anthony D. Woolf,Abdulhalik Workicho,Denis Xavier,Gelin Xu,Simon Yadgir,Mohsen Yaghoubi,Bereket Yakob,Lijing L Yan,Yuichiro Yano,Pengpeng Ye,Hassen Hamid Yimam,Paul S. F. Yip,Naohiro Yonemoto,Seok Jun Yoon,Marcel Yotebieng,Mustafa Z. Younis,Mustafa Z. Younis,Zoubida Zaidi,Maysaa El Sayed Zaki,Elias Asfaw Zegeye,Zerihun Menlkalew Zenebe,Xueying Zhang,Maigeng Zhou,Ben Zipkin,Sanjay Zodpey,Liesl Zühlke,Christopher J L Murray +778 more
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016.
Journal ArticleDOI
Global, regional, and national incidence, prevalence, andyears lived with disability for 354 diseases and injuries for195 countries and territories, 1990–2017: a systematicanalysis for the Global Burden of Disease Study 2017
Gbd Disease,Injury Incidence,Lorenzo Monasta,Luca Ronfani,Ettore Beghi,Giorgia Giussani,Boris Bikbov,Norberto Perico,Cristina Bosetti,Monica Cortinovis,Silvano Gallus,Giuseppe Remuzzi +11 more
TL;DR: All-cause age-standardised YLD rates decreased by 3·9% from 1990 to 2017; however, the all-age YLD rate increased by 7·2% while the total sum of global YLDs increased from 562 million (421–723) to 853 million (642–1100).
Journal ArticleDOI
Decision making with the analytic hierarchy process
TL;DR: The Analytic Hierarchy Process (AHP) is a theory of measurement through pairwise comparisons and relies on the judgements of experts to derive priority scales that measure intangibles in relative terms.
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Decision Making with the Analytic Hierarchy Process
TL;DR: The Analytic Hierarchy Process (AHP) as discussed by the authors is a theory of measurement through pairwise comparisons and relies on the judgements of experts to derive priority scales, these scales are these scales that measure intangibles in relative terms.
Journal ArticleDOI
IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045.
Nam H. Cho,Nam H. Cho,Jonathan E. Shaw,Suvi Karuranga,Yadi Huang,J. D. da Rocha Fernandes,A.W. Ohlrogge,Belma Malanda +7 more
TL;DR: The new estimates of diabetes prevalence, deaths attributable to diabetes and healthcare expenditure due to diabetes present a large social, financial and health system burden across the world.