S
Steven P. Gygi
Researcher at Harvard University
Publications - 778
Citations - 147003
Steven P. Gygi is an academic researcher from Harvard University. The author has contributed to research in topics: Proteome & Phosphorylation. The author has an hindex of 172, co-authored 704 publications receiving 129173 citations. Previous affiliations of Steven P. Gygi include University of Rochester Medical Center & Cell Signaling Technology.
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Temporal Proteomic Profiling of SH-SY5Y Differentiation with Retinoic Acid Using FAIMS and Real-Time Searching.
TL;DR: This work quantitatively profiled over 9400 proteins across a 7-day treatment with retinoic acid using state-of-the-art mass spectrometry-based proteomics technologies, including FAIMS, real-time database searching, and TMTpro16 sample multiplexing, and observed multiple patterns among the queried proteins.
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Characterization of Plasmodium falciparum Atypical Kinase PfPK7– Dependent Phosphoproteome
Brittany N. Pease,Edward L. Huttlin,Mark P. Jedrychowski,Dominique Dorin-Semblat,Daniela Sebastiani,Daniel T. Segarra,Bracken F. Roberts,Ratna Chakrabarti,Christian Doerig,Steven P. Gygi,Debopam Chakrabarti +10 more
TL;DR: In this paper, the authors performed isobaric tag-based quantitative comparative phosphoproteomics of the schizont and segmenter stages from wild-type and pfpk7- parasite lines.
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A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin
TL;DR: It is shown that the Rix1-associated complex, which contains RNA endonuclease and polynucleotide kinase activities with known roles in ribosomal RNA processing, is required for spreading and epigenetic inheritance of heterochromatin in fission yeast.
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The influence of signals from chilled roots on the proteome of shoot tissues in rice seedlings
Karlie A. Neilson,Andrew P. Scafaro,Joel M. Chick,Iniga S. George,Steven C. Van Sluyter,Steven P. Gygi,Brian J. Atwell,Paul A. Haynes +7 more
TL;DR: This study imposed chilling temperatures on roots of rice plants while maintaining shoots at optimum atmospheric temperature to study the effect of root chilling on the global protein expression in shoots and found evidence of a possible induction of a sugar signalling pathway.
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ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection.
Elijah L. Mena,Callie J Donahue,Laura Pontano Vaites,Jie Li,Gergely Róna,Gergely Róna,Colin O’Leary,Luca Lignitto,Bearach Miwatani-Minter,Joao A. Paulo,Avantika Dhabaria,Beatrix Ueberheide,Steven P. Gygi,Michele Pagano,Michele Pagano,J. Wade Harper,Robert A. Davey,Stephen J. Elledge +17 more
TL;DR: In this article, the N terminus of ORF10 was found to be critical for the ORF-ZYG11B interaction and showed that it is not relevant for SARS-CoV-2 infection.