T
Tae Hwi Schwantes-An
Researcher at National Institutes of Health
Publications - 8
Citations - 396
Tae Hwi Schwantes-An is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 7, co-authored 7 publications receiving 350 citations. Previous affiliations of Tae Hwi Schwantes-An include Washington University in St. Louis & Indiana University.
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Journal ArticleDOI
Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error
Qiao Fan,Qiao Fan,Virginie J. M. Verhoeven,Robert Wojciechowski,Robert Wojciechowski,Veluchamy A. Barathi,Pirro G. Hysi,Jeremy A. Guggenheim,René Höhn,René Höhn,Veronique Vitart,Anthony P Khawaja,Kenji Yamashiro,S. Mohsen Hosseini,Terho Lehtimäki,Yi Lu,Toomas Haller,Jing Xie,Cécile Delcourt,Mario Pirastu,Juho Wedenoja,Puya Gharahkhani,Cristina Venturini,Cristina Venturini,Masahiro Miyake,Alex W. Hewitt,Alex W. Hewitt,Xiaobo Guo,Johanna Mazur,Jenifer E. Huffman,Katie M Williams,Ozren Polasek,Harry Campbell,Igor Rudan,Zoran Vatavuk,James F. Wilson,Peter K. Joshi,George McMahon,Beate St Pourcain,David M. Evans,David M. Evans,Claire L. Simpson,Tae Hwi Schwantes-An,Robert P. Igo,Alireza Mirshahi,Audrey Cougnard-Gregoire,Céline Bellenguez,Maria Blettner,Olli T. Raitakari,Mika Kähönen,Ilkka Seppälä,Tanja Zeller,Thomas Meitinger,Janina S. Ried,Christian Gieger,Laura Portas,Elisabeth M. van Leeuwen,Najaf Amin,André G. Uitterlinden,Fernando Rivadeneira,Albert Hofman,Johannes R. Vingerling,Ya Xing Wang,Xu Wang,Eileen Tai-Hui Boh,M. Kamran Ikram,M. Kamran Ikram,Charumathi Sabanayagam,Charumathi Sabanayagam,Preeti Gupta,Vincent Tan,Lei Zhou,Candice E H Ho,Wan’E. Lim,Roger W. Beuerman,Rosalynn Grace Siantar,Rosalynn Grace Siantar,E. Shyong Tai,Eranga N. Vithana,Evelin Mihailov,Chiea Chuen Khor,Chiea Chuen Khor,Chiea Chuen Khor,Caroline Hayward,Robert Luben,Paul J. Foster,Barbara E.K. Klein,Ronald Klein,Hoi Suen Wong,Paul Mitchell,Andres Metspalu,Tin Aung,Tin Aung,Terri L. Young,Mingguang He,Olavi Pärssinen,Cornelia M. van Duijn,Jie Jin Wang,Cathy Williams,Jost B. Jonas,Jost B. Jonas,Yik Ying Teo,David A. Mackey,David A. Mackey,Konrad Oexle,Nagahisa Yoshimura,Andrew D. Paterson,Norbert Pfeiffer,Tien Yin Wong,Paul N. Baird,Dwight Stambolian,Joan E. Bailey Wilson,Ching-Yu Cheng,Ching-Yu Cheng,Christopher J Hammond,Caroline C W Klaver,Seang-Mei Saw,Jugnoo S Rahi,Jugnoo S Rahi,Jean-François Korobelnik,Jean-François Korobelnik,John P. Kemp,Nicholas J. Timpson,George Davey Smith,Jamie E Craig,Kathryn P. Burdon,Rhys Fogarty,Sudha K. Iyengar,Emily Y. Chew,Sarayut Janmahasatian,Nicholas G. Martin,Stuart MacGregor,Liang Xu,Maria Schache,Vinay Nangia,Songhomitra Panda-Jonas,Alan F. Wright,Jeremy Fondran,Jonathan H. Lass,Sheng Feng,Jing Hua Zhao,Kay-Tee Khaw,Nicholas J. Wareham,Taina Rantanen,Jaakko Kaprio,Jaakko Kaprio,Chi Pui Pang,Li Jia Chen,Pancy O. S. Tam,Vishal Jhanji,Alvin L. Young,Angela Döring,Leslie J. Raffel,Mary Frances Cotch,Xiaohui Li,Shea Ping Yip,Maurice Yap,Ginevra Biino,Simona Vaccargiu,Maurizio Fossarello,Brian W Fleck,Seyhan Yazar,Seyhan Yazar,Jan Willem L Tideman,Milly S. Tedja,Margaret M. DeAngelis,Margaux A. Morrison,Lindsay A. Farrer,Xiangtian Zhou,Wei Chen,Nobuhisa Mizuki,Akira Meguro,Kari-Matti Mäkelä +172 more
TL;DR: Six novel loci (FAM150B-ACP1, LINC00340, FBN1, DIS3L-MAP2K1, ARID2-SNAT1 and SLC14A2) associated with refractive error are identified and represent an important advance in understanding how gene and environment interactions contribute to the heterogeneity of myopia.
Journal ArticleDOI
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts
Tae Hwi Schwantes-An,Tae Hwi Schwantes-An,Juan Zhang,Juan Zhang,Li-Shiun Chen,Sarah M. Hartz,Robert Culverhouse,Xiangning Chen,Hilary Coon,Josef Frank,Helen M. Kamens,Helen M. Kamens,Bettina Konte,Leena Kovanen,Antti Latvala,Lisa N. Legrand,Brion S. Maher,Whitney E. Melroy,Elliot C. Nelson,Mark W. Reid,Jason D. Robinson,Pei Hong Shen,Bao-Zhu Yang,Judy A. Andrews,Paul Aveyard,Olga Beltcheva,Sandra A. Brown,Dale S. Cannon,Sven Cichon,Sven Cichon,Robin P. Corley,Norbert Dahmen,Louisa Degenhardt,Louisa Degenhardt,Tatiana Foroud,Wolfgang Gaebel,Ina Giegling,Stephen J. Glatt,Richard A. Grucza,Jill Hardin,Annette M. Hartmann,Andrew C. Heath,Stefan Herms,Stefan Herms,Colin A. Hodgkinson,Per Hoffmann,Per Hoffmann,Hyman Hops,David Huizinga,Marcus Ising,Eric O. Johnson,Elaine C. Johnstone,Radka Kaneva,Kenneth S. Kendler,Falk Kiefer,Henry R. Kranzler,Kenneth Krauter,Orna Levran,Susanne Lucae,Michael T. Lynskey,Wolfgang Maier,Karl Mann,Nicholas G. Martin,Manuel Mattheisen,Manuel Mattheisen,Manuel Mattheisen,Grant W. Montgomery,Bertram Müller-Myhsok,Michael F. Murphy,Michael C. Neale,Momchil Nikolov,Momchil Nikolov,Denise Nishita,Markus M. Nöthen,John I. Nurnberger,Timo Partonen,Michele L. Pergadia,Maureen Reynolds,Monika Ridinger,Richard J. Rose,Noora Rouvinen-Lagerström,Norbert Scherbaum,Christine Schmäl,Michael Soyka,Michael C. Stallings,Michael Steffens,Jens Treutlein,Ming T. Tsuang,Tamara L. Wall,Norbert Wodarz,Vadim Yuferov,Peter Zill,Andrew W. Bergen,Jingchun Chen,Paul M. Cinciripini,Howard J. Edenberg,Marissa A. Ehringer,Robert E. Ferrell,Joel Gelernter,David Goldman,John K. Hewitt,Christian J. Hopfer,William G. Iacono,Jaakko Kaprio,Jaakko Kaprio,Mary Jeanne Kreek,Ivo Kremensky,Pamela A. F. Madden,Matt McGue,Marcus R. Munafò,Robert A. Philibert,Marcella Rietschel,Alec Roy,Dan Rujescu,Sirkku T. Saarikoski,Gary E. Swan,Alexandre A. Todorov,Michael M. Vanyukov,Robert B. Weiss,Laura J. Bierut,Nancy L. Saccone +120 more
TL;DR: In this article, the non-synonymous variant of the mu1 opioid receptor gene (A118G, Asn40Asp) has been extensively studied, yet its role in addiction has remained unclear, with conflicting association findings.
Journal ArticleDOI
Smoking and Genetic Risk Variation Across Populations of European, Asian, and African American Ancestry—A Meta‐Analysis of Chromosome 15q25
Li-Shiun Chen,Nancy L. Saccone,Robert Culverhouse,Paige M. Bracci,Chien Hsiun Chen,Nicole Dueker,Younghun Han,Hongyan Huang,Guangfu Jin,Takashi Kohno,Jennie Z. Ma,Thomas R. Przybeck,Alan R. Sanders,Jennifer A. Smith,Yun Ju Sung,Angie S. Wenzlaff,Chen Wu,Dankyu Yoon,Ying Ting Chen,Yu-Ching Cheng,Yoon Shin Cho,Sean P. David,Sean P. David,Sean P. David,Jubao Duan,Charles B. Eaton,Helena Furberg,Alison Goate,Dongfeng Gu,Helen M. Hansen,Sarah M. Hartz,Zhibin Hu,Young Jin Kim,Young Jin Kim,Steven J. Kittner,Douglas F. Levinson,Thomas H. Mosley,Thomas J. Payne,D. C. Rao,John P. Rice,Treva Rice,Tae Hwi Schwantes-An,Sanjay Shete,Jianxin Shi,Margaret R. Spitz,Yan V. Sun,Fuu Jen Tsai,Jen C. Wang,Margaret Wrensch,Hong Xian,Pablo V. Gejman,Jiang He,Steven C. Hunt,Sharon L.R. Kardia,Ming D. Li,Dongxin Lin,Braxton D. Mitchell,Taesung Park,Ann G. Schwartz,Hongbing Shen,John K. Wiencke,Jer-Yuarn Wu,Jun Yokota,Christopher I. Amos,Laura J. Bierut +64 more
TL;DR: In this paper, the observed consistent association of rs16969968 with heavy smoking across multiple populations, combined with its known biological significance, suggests it is most likely a functional variant that alters risk for heavy smoking.
Journal ArticleDOI
Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers
Sarah M. Hartz,Susan E. Short,Nancy L. Saccone,Robert Culverhouse,Li-Shiun Chen,Tae Hwi Schwantes-An,Hilary Coon,Younghun Han,Sarah H. Stephens,Juzhong Sun,Xiangning Chen,Francesca Ducci,Francesca Ducci,Nicole Dueker,Nora Franceschini,Josef Frank,Frank Geller,Daniel Guobjartsson,Nadia N. Hansel,Chenhui Jiang,Kaisu Keskitalo-Vuokko,Zhen Liu,Leo-Pekka Lyytikäinen,Martha Michel,Rajesh Rawal,Albert Rosenberger,Paul Scheet,John R. Shaffer,Alexander Teumer,John R. Thompson,Jacqueline M. Vink,Nicole Vogelzangs,Angela S. Wenzlaff,William Wheeler,Xiangjun Xiao,Bao-Zhu Yang,Steven H. Aggen,Anthony J. Balmforth,Sebastian E. Baumeister,Terri H. Beaty,Siiri N. Bennett,Andrew W. Bergen,Heather A. Boyd,Ulla Broms,Ulla Broms,Harry Campbell,Nilanjan Chatterjee,Jingchun Chen,Yu-Ching Cheng,Sven Cichon,David Couper,Francesco Cucca,Danielle M. Dick,Tatiana Foroud,Helena Furberg,Ina Giegling,Fangyi Gu,Alistair S. Hall,Jenni Hällfors,Shizhong Han,Annette M. Hartmann,Caroline Hayward,Kauko Heikkilä,John K. Hewitt,Jouke-Jan Hottenga,Majken K. Jensen,Pekka Jousilahti,Marika Kaakinen,Steven J. Kittner,Bettina Konte,Tellervo Korhonen,Maria Teresa Landi,Tiina Laatikainen,Mark Leppert,Steven M. Levy,Rasika A. Mathias,Daniel W. McNeil,Sarah E. Medland,Grant W. Montgomery,Thomas Muley,Tanda Murray,Matthias Nauck,Kari E. North,Michele L. Pergadia,Ozren Polasek,Erin M. Ramos,Samuli Ripatti,Angela Risch,Ingo Ruczinski,Igor Rudan,Veikko Salomaa,David Schlessinger,Unnur Styrkarsdottir,Antonio Terracciano,Manuela Uda,Gonneke Willemsen,Xifeng Wu,Gonçalo R. Abecasis,Kathleen C. Barnes,Heike Bickeböller,Eric Boerwinkle,Dorret I. Boomsma,Neil E. Caporaso,Jubao Duan,Howard J. Edenberg,Clyde Francks,Pablo V. Gejman,Joel Gelernter,Hans J. Grabe,Hyman Hops,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Jorma Viikari,Mika Kähönen,Kenneth S. Kendler,Terho Lehtimäki,Douglas F. Levinson,Mary L. Marazita,Jonathan Marchini,Mads Melbye,Braxton D. Mitchell,Jeffrey C. Murray,Markus M. Nöthen,Brenda W.J.H. Penninx,Olli T. Raitakari,Marcella Rietschel,Dan Rujescu,Nilesh J. Samani,Alan R. Sanders,Ann G. Schwartz,Sanjay Shete,Jianxin Shi,Margaret R. Spitz,Kari Stefansson,Gary E. Swan,Thorgeir E. Thorgeirsson,Henry Völzke,Qingyi Wei,H.-Erich Wichmann,Christopher I. Amos,Naomi Breslau,Dale S. Cannon,Marissa A. Ehringer,Richard A. Grucza,Dorothy K. Hatsukami,Andrew C. Heath,Eric O. Johnson,Jaakko Kaprio,Jaakko Kaprio,Pamela A. F. Madden,Nicholas G. Martin,Victoria L. Stevens,Jerry A. Stitzel,Robert B. Weiss,Peter Kraft,Laura J. Bierut +156 more
TL;DR: In this article, the association between rs16969968 and smoking is modified by age at onset of regular smoking, which highlights an increased genetic vulnerability to smoking in early-onset smokers.
Journal ArticleDOI
8q24 risk alleles and prostate cancer in African-Barbadian men.
Cheryl D. Cropp,Christiane M. Robbins,Xin Sheng,Anselm Hennis,John D. Carpten,Lyndon Waterman,Ronald Worrell,Tae Hwi Schwantes-An,Jeffrey M. Trent,Christopher A. Haiman,M. Cristina Leske,Suh Yuh Wu,Joan E. Bailey-Wilson,Barbara Nemesure +13 more
TL;DR: This investigation is to evaluate the association between previously reported 8q24 risk alleles and PRCA in African‐Barbadian men known to have high rates of PRCA.