Institution
California Institute of Technology
Education•Pasadena, California, United States•
About: California Institute of Technology is a education organization based out in Pasadena, California, United States. It is known for research contribution in the topics: Galaxy & Redshift. The organization has 57649 authors who have published 146691 publications receiving 8620287 citations. The organization is also known as: Caltech & Cal Tech.
Topics: Galaxy, Redshift, Population, Star formation, Stars
Papers published on a yearly basis
Papers
More filters
TL;DR: A tutorial introduction to the complex structured singular value (μ) is presented, with an emphasis on the mathematical aspects of μ.
1,515 citations
TL;DR: A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here and reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.
Abstract: Development of the body plan is controlled by large networks of regulatory genes. A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here. The network was derived from large-scale perturbation analyses, in combination with computational methodologies, genomic data, cis-regulatory analysis, and molecular embryology. The network contains over 40 genes at present, and each node can be directly verified at the DNA sequence level by cis-regulatory analysis. Its architecture reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.
1,515 citations
TL;DR: A clone encoding PrP 27-30, the major protein in purified preparations of scrapie agent, was selected from a scrapie-infected hamster brain cDNA library by oligonucleotide probes corresponding to the N terminus of the protein.
1,514 citations
1,513 citations
Joint Genome Institute1, University of Oxford2, University of St Andrews3, Washington University in St. Louis4, University of California, Berkeley5, Swiss Institute of Bioinformatics6, University of Lausanne7, Kyoto University8, California Institute of Technology9, National Institute for Medical Research10, University of Barcelona11, Children's Hospital Oakland12, Genetic Information Research Institute13, National Institute of Genetics14, Stanford University15, National Institute of Informatics16, University of California, San Diego17
TL;DR: Whole-genome comparisons illuminate the murky relationships among the three chordate groups (tunicates, lancelets and vertebrates), and allow not only reconstruction of the gene complement of the last common chordate ancestor but also partial reconstruction of its genomic organization.
Abstract: Lancelets ('amphioxus') are the modern survivors of an ancient chordate lineage, with a fossil record dating back to the Cambrian period. Here we describe the structure and gene content of the highly polymorphic approximately 520-megabase genome of the Florida lancelet Branchiostoma floridae, and analyse it in the context of chordate evolution. Whole-genome comparisons illuminate the murky relationships among the three chordate groups (tunicates, lancelets and vertebrates), and allow not only reconstruction of the gene complement of the last common chordate ancestor but also partial reconstruction of its genomic organization, as well as a description of two genome-wide duplications and subsequent reorganizations in the vertebrate lineage. These genome-scale events shaped the vertebrate genome and provided additional genetic variation for exploitation during vertebrate evolution.
1,513 citations
Authors
Showing all 58155 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Eric S. Lander | 301 | 826 | 525976 |
| Donald P. Schneider | 242 | 1622 | 263641 |
| George M. Whitesides | 240 | 1739 | 269833 |
| Yi Chen | 217 | 4342 | 293080 |
| David Baltimore | 203 | 876 | 162955 |
| Edward Witten | 202 | 602 | 204199 |
| George Efstathiou | 187 | 637 | 156228 |
| Michael A. Strauss | 185 | 1688 | 208506 |
| Jing Wang | 184 | 4046 | 202769 |
| Ruedi Aebersold | 182 | 879 | 141881 |
| Douglas Scott | 178 | 1111 | 185229 |
| Hyun-Chul Kim | 176 | 4076 | 183227 |
| Phillip A. Sharp | 172 | 614 | 117126 |
| Timothy M. Heckman | 170 | 754 | 141237 |
| Zhenan Bao | 169 | 865 | 106571 |