Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Polymers in Metal–Organic Frameworks: From Nanostructured Chain Assemblies to New Functional Materials
Takashi Kitao,Takashi Uemura +1 more
TL;DR: In this paper, the authors present a highlight review of metal-organic frameworks (MOFs) for controlling polymer assemblies, focusing on the characteristic features of MOFs such as their highly tailorable and robustness.
Journal ArticleDOI
Charge-switchable MOF nanocomplex for enhanced biofilm penetration and eradication
TL;DR: In this article , a charge-switchable and pH-responsive nanocomplex is fabricated via a facile aqueous one-pot zeolitic imidazolate framework-8 (ZIF-8) encapsulation of proteinase K (PK) and photosensitizer Rose Bengal (RB), for enzymatic and photodynamic therapies (PDT) against biofilm infections.
Journal ArticleDOI
Metal-nucleobase hybrid nanoparticles for enhancing the activity and stability of metal-activated enzymes.
TL;DR: Despite the lack of active Mg2+ ions, methionine adenosyltransferase (MAT) immobilized by Zn2(adenine) still exhibited robust catalytic activity and stability at pH 3 and 80 °C.
Journal ArticleDOI
Encapsulation of collagenase within biomimetically mineralized metal–organic frameworks: designing biocomposites to prevent collagen degradation
Odair Bim Júnior,Ana K. Bedran-Russo,Jader Barbosa Silva Flor,Ana Flávia Sanches Borges,Valdecir Farias Ximenes,Regina Célia Galvão Frem,Paulo Noronha Lisboa-Filho +6 more
TL;DR: Collagen-degrading enzyme induced rapid formation of a metal–organic framework (ZIF-8) as a protective shell, which afforded the control of the enzyme's bioactivity.
Journal ArticleDOI
Amidinium⋯carboxylate frameworks: predictable, robust, water-stable hydrogen bonded materials
TL;DR: In the last few years, the amidinium-carboxylate interaction has emerged as a powerful tool for the relatively predictable construction of families of three dimensional hydrogen-bonded organic frameworks.
References
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The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
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Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
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Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
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The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
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Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.