Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
Citations
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Self-Assembly of Copper–DNAzyme Nanohybrids for Dual-Catalytic Tumor Therapy
Congzhi Liu,Congzhi Liu,Yao-Xuan Chen,Yao-Xuan Chen,Jian Zhao,Jian Zhao,Yong Wang,Yulei Shao,Yulei Shao,Zhanjun Gu,Lele Li,Lele Li,Yuliang Zhao,Yuliang Zhao +13 more
TL;DR: In this paper, the authors developed a simple approach for the synthesis of hybrid nanostructures that exclusively consist of DNAzyme and Cu2+ with ultra-high loading capacity for combinational catalytic therapy.
Journal ArticleDOI
Aptamer-Embedded Zirconium-Based Metal–Organic Framework Composites Prepared by De Novo Bio-Inspired Approach with Enhanced Biosensing for Detecting Trace Analytes
Zhihong Zhang,Fenghe Duan,Jia-Yue Tian,Jun-Ying He,Longyu Yang,Hui Zhao,Shuai Zhang,Chun-Sen Liu,Linghao He,Min Chen,Di-Ming Chen,Miao Du +11 more
TL;DR: A series of Zr-based metal-organic framework (MOF) composites embedded with three kinds of aptamer strands (509-MOF@Apt) were achieved by a one-step de novo synthetic approach to provide a new platform for direct and feasible detection in biosensing related to clinical diagnostics and therapeutics, and extend the scope of potential applications for MOF materials.
Journal ArticleDOI
Improvement of Biological Organisms Using Functional Material Shells
TL;DR: In this article, the authors reviewed recent achievements of organism improvements by various material shells and related applications in cell protection, storage, thermal stability, biological stealth, photosynthesis and biocatalysis.
Journal ArticleDOI
Iodine-loaded metal organic framework as growth-triggered antimicrobial agent
Ai-Nhan Au-Duong,Cheng-Kang Lee +1 more
TL;DR: The result demonstrates that iodine was released from the disintegrated ZIF-8@I to kill bacteria in response to the bacterial growth-induced pH lowering and showed its acidic pH-triggered antimicrobial activity against deposited bacterial cells.
Journal ArticleDOI
Semi-crystalline Fe-BTC MOF material as an efficient support for enzyme immobilization
TL;DR: This work presents a systematic study of the semi-crystalline Fe-BTC MOF material (commercialized as Basolite F300) employed as support of the enzymes laccase and lipase through either in-situ or post-synthesis methodology.
References
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The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
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Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
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Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
Journal ArticleDOI
Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.