Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Metal-organic frameworks functionalized with nucleic acids and amino acids for structure- and function-specific applications: A tutorial review
TL;DR: This work demonstrates the progress of MOF biofunctionalization with nucleic acid- (ssDNA, ds DNA, and aptamer) and amino acid-based biomolecules (single amino acid, peptide, and protein) for various structure- and function-specific applications.
Journal ArticleDOI
The biomineralization process of uranium(VI) by Saccharomyces cerevisiae — transformation from amorphous U(VI) to crystalline chernikovite
TL;DR: An understanding of the non-reductive transformation process of U(VI) from the amorphous to crystalline state within microbe systems, which would be beneficial for the U( VI) treatment and reuse of nuclides and heavy metals is provided.
Journal ArticleDOI
Amino acids as biomimetic crystallization agents for the synthesis of ZIF-8 particles
TL;DR: The morphology, size, and particle number of resultant MOF crystals were strongly dependent on the chemical nature of amino acid side chains that match closely the four classes of amino acids: nonpolar, polar neutral, polar negative and polar positive.
Journal ArticleDOI
Composition Engineered Metal-Organic-Framework-Based Microneedles for Glucose-Mediated Transdermal Insulin Delivery
TL;DR: A new strategy, using facilely synthesized MOF as depots to integrate with MNs, for designing stimuli-responsive transdermal drug delivery systems, which showed good dependence on glucose concentration without divulging H2O2 and Co2+ ions and enough stiffness to penetrate into skin.
Journal ArticleDOI
Enzyme immobilization on ZIF-67/MWCNT composite engenders high sensitivity electrochemical sensing
TL;DR: In this paper, new strategies have been presented: (i) using MOFs that themselves possess catalytic properties for substrates, so the synergistic catalysis by combining the MOFs and immobilized enzymes can be reinforced; (ii) introducing hydrophilic carbon nanomaterials and preparing MOF/carbon composites, not only the conductivity of the matrix but also the apparent affinity of immobilized enzyme for hydrophilic substrate can be remarkably enhanced.
References
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The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
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Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
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Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
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Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.