Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Imparting Designer Biorecognition Functionality to Metal-Organic Frameworks by a DNA-Mediated Surface Engineering Strategy.
Weiyu Ning,Zhenghan Di,Yingjie Yu,Pingmei Zeng,Chunzhi Di,Daquan Chen,Xueqian Kong,Guangjun Nie,Yuliang Zhao,Lele Li +9 more
TL;DR: The results suggest that the strategy allows for surface functionalization of MOFs with different functional DNAs, extending the use of these materials to diverse applications in biosensor, bioimaging, and nanomedicine.
Journal ArticleDOI
Biomimetic Copper-Based Inorganic–Protein Nanoflower Assembly Constructed on the Nanoscale Fibrous Membrane with Enhanced Stability and Durability
Mufang Li,Mengying Luo,Li Fei,Wenwen Wang,Ke Liu,Qiongzhen Liu,Yuedan Wang,Lu Zhentan,Dong Wang +8 more
TL;DR: In this article, the structure, morphology, and crystallization of the copper-based inorganic-protein nanoflowers were analyzed, which led to a formation mechanism of the hybrid nanoflower.
Journal ArticleDOI
Protein-directed, hydrogen-bonded biohybrid framework
Guosheng Chen,Siming Huang,Yong Shen,Xiaoxue Kou,Xiaomin Ma,Shuyao Huang,Qing Tong,Kaili Ma,Wen Chen,Peiyi Wang,Jun Shen,Fang Zhu,Gangfeng Ouyang +12 more
TL;DR: A versatile protein-directed assembly strategy that enables the organization of different types of proteins and organic linkers into a highly crystalline hybrid framework through hydrogen-bond interaction is described, and the obtained enzyme framework shows significantly improved stability compared with the free enzymes.
Journal ArticleDOI
Metal‐Organic Framework Encapsulation Preserves the Bioactivity of Protein Therapeutics
Congzhou Wang,Gail Sudlow,Zheyu Wang,Sisi Cao,Qisheng Jiang,Alicia Neiner,Jeremiah J. Morrissey,Evan D. Kharasch,Samuel Achilefu,Srikanth Singamaneni +9 more
TL;DR: A facile approach using a nanoporous material, zeolitic imidazolate framework‐8 (ZIF‐8), as an encapsulant for preserving the prototypic protein therapeutic, insulin, against different harsh conditions that may be encountered during storage, formulation, and transport, including elevated temperatures, mechanical agitation, and organic solvent is reported.
Journal ArticleDOI
Biopolymer@Metal-Organic Framework Hybrid Materials: A Critical Survey
TL;DR: In this article, a review article spotlights the fashionable trend in bridging the field of MOF-based materials through the use of bio-based precursors (mainly biopolymers) and discusses how the holistic association of the MOF crystals and the biopolymer matrices resulted in promising materials with prominent properties.
References
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Journal ArticleDOI
The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
Journal ArticleDOI
Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
Journal ArticleDOI
Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
Journal ArticleDOI
Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.