Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Immunotherapy of tumors by tailored nano-zeolitic imidazolate framework protected biopharmaceuticals.
TL;DR: In this article, the authors discussed the mechanistic window of antibody delivery-based immunotherapy via the encapsulation of antibodies within ZIFs as an emerging tool for protecting biopharmaceuticals from the complex cellular microenvironment and hyperthermia to enable an antitumor immune response.
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Recent advances in nanoarchitectures of monocrystalline coordination polymers through confined assembly
TL;DR: In this article , a short review of recent advances in nano-architectures based on monocrystalline coordination polymers that are formed through confined assembly is presented, where the authors discuss the properties of the coordination polymer single crystals as well as their performance in energy, environmental, and biomedical applications.
Journal ArticleDOI
A comprehensive review on bio‐mimicked multimolecular frameworks and supramolecules as scaffolds for enzyme immobilization
Shalu Aggarwal,Saiqa Ikram +1 more
TL;DR: The potential synergies between artificial supramolecular structures and biological systems are discussed in this paper , where the authors emphasize the possibilities of associating multimolecular complexes with biological entities via several types of interactions, namely covalent interactions, host-guest complexation, π − π ${\rm{\pi }}-{\rm{\π }}$ interactions, intra/inter hydrogen bondings, electrostatic interactions, and so forth.
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An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability.
Ernesto Soto,Charles A. Specht,Florentina Rus,Chrono K. Lee,Ambily Abraham,Stuart M. Levitz,Gary R. Ostroff +6 more
TL;DR: In this paper , an efficient protein encapsulation approach using tetraethylorthosilicate (TEOS) to lock protein payloads in a thermostable silica cage formed inside the hollow cavity of Glucan particles (GPs) is presented.
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Metal-Organic Frameworks in Microfluidics Enable Fast Encapsulation/Extraction of DNA for Automated and Integrated Data Storage.
Cuiping Mao,Shuchen Wang,Jiankai Li,Zhuowei Feng,Tong Zhang,Rui Qing Wang,Chunhai Fan,Xingyu Jiang +7 more
TL;DR: In this paper , a DNA micro library can be encapsulated by metal-organic frameworks (MOFs) within 10 min and extracted (5 min) in a single microfluidic chip for automated and integrated DNA-based data storage.
References
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The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
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Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
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Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
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Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.