Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
Citations
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Integration of Biomolecules with Metal–Organic Frameworks
TL;DR: By optimizing biomolecule integration methods while overcoming existing challenges, biomolecular-integrated MOF platforms are very promising to generate more practical applications.
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An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong humoral and cellular immune responses.
Xiaofang Zhong,Yunting Zhang,Lu Tan,Tao Zheng,Y.P. Hou,Xiaoyu Hong,Guangsheng Du,Xiao Yan Chen,Yuandong Zhang,Xun Sun +9 more
TL;DR: It is demonstrated that ZANPs may be a safe and effective vehicle for the development of cancer vaccines by taking advantage of a natural biomineralization process to create aluminum-containing nanoZIF-8 particles for antigen delivery.
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Polyphenol-Based Particles for Theranostics.
TL;DR: This review summary summarizes the assembly of polyphenol-based particles, including polydopamine (PDA) particles, metal-phenolic network (MPN)-based particle, and polymer-phenol particles, and their potential biomedical applications in various diagnostic and therapeutic applications.
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Metal and Metal Oxide Nanoparticles to Enhance the Performance of Enzyme-Linked Immunosorbent Assay (ELISA)
TL;DR: Enzyme-linked immunosorbent assay (ELISA) is a technique designed for the detection and quantification of (bio)molecules in a liquid sample as discussed by the authors.
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Carbonic Anhydrase Enzyme-MOFs Composite with a Superior Catalytic Performance to Promote CO2 Absorption into Tertiary Amine Solution.
TL;DR: The analyses of Fourier transform infrared spectroscopy and circular dichroism revealed that the CA enzyme's secondary structure was not significantly varied during the CA/ZIF-L-1 preparation, resulting in a high enzyme activity retention, and can be a good candidate to promote the CO2 capture in industrial application.
References
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Journal ArticleDOI
The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
Journal ArticleDOI
Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
Journal ArticleDOI
Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
Journal ArticleDOI
Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.