Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Structure Optimisation of Large Transition‐Metal Complexes with Extended Tight‐Binding Methods
TL;DR: The capability of the recently developed GFNn-xTB method family for full quantum mechanical geometry optimisation of medium to very large transition metal complexes and organometallic supramolecular structures is reported on.
Journal ArticleDOI
Direct Observation of Amorphous Precursor Phases in the Nucleation of Protein–Metal–Organic Frameworks
Alana F. Ogata,Alexander M. Rakowski,Brooke P Carpenter,Dmitry A. Fishman,Jovany G. Merham,Paul J. Hurst,Joseph P. Patterson +6 more
TL;DR: The structural evolution of p-MOFs was probed by cryo-transmission electron microscopy, revealing nonclassical pathways via dissolution-recrystallization of highly hydrated amorphous particles and solid-state transformation of a protein-rich amorphus phase.
Journal ArticleDOI
In situ and post-synthesis immobilization of enzymes on nanocrystalline MOF platforms to yield active biocatalysts
TL;DR: In this article, the Spanish State Research Agency (Agencia Espanola de Investigacion, AEI) and the European Regional Development Fund (Fondo Europeo de Desarrollo Regional, FEDER) through the Project MAT2016•77496•R (AEI/FEDER, UE).
Journal ArticleDOI
Biomimetic Metal-Organic Framework Composite-Mediated Cascade Catalysis for Synergistic Bacteria Killing.
Xiqing Cheng,Shuai Zhang,Huihui Liu,Hanming Chen,Jinhong Zhou,Zhiwei Chen,Xi Zhou,Zhaoxiong Xie,Qin Kuang,Lan-Sun Zheng +9 more
TL;DR: A novel MOF composite biomimetic structure based on co-encapsulation of glucose oxidase and L-arginine into Cu-MOFs (CuBDC) with Fenton-like catalytic activity is designed for achieving synergistic antibacterial effect and proposes a new design idea for highly efficient antibiosis as well as even therapy of tumors.
Journal ArticleDOI
Bioinspired Design of Fe3+‐Doped Mesoporous Carbon Nanospheres for Enhanced Nanozyme Activity
TL;DR: A biomimetic strategy was developed to design Fe3+ -doped mesoporous carbon nanospheres as a horseradish peroxidase (HRP) mimic to realize the structure and function mimicking of natural HRP.
References
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Journal ArticleDOI
The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
Journal ArticleDOI
Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
Journal ArticleDOI
Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
Journal ArticleDOI
Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.