Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules.
Kang Liang,Raffaele Ricco,Cara M. Doherty,Mark J. Styles,Stephen Bell,Nigel Kirby,Stephen T. Mudie,David N. Haylock,Anita J. Hill,Christian J. Doonan,Paolo Falcaro +10 more
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TLDR
It is shown that proteins, enzymes and DNA rapidly induce the formation of protective metal-organic framework coatings under physiological conditions by concentrating the framework building blocks and facilitating crystallization around the biomacromolecules.Abstract:
Robust biomacromolecules could be used for a wide range of biotechnological applications. Here the authors report a biomimetic mineralization process, in which biomolecules are encapsulated within metal-organic frameworks, and their stability is subsequently increased without significant bioactivity loss.read more
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Specific Ligation of Two Multimeric Enzymes with Native Peptides and Immobilization with Controlled Molar Ratio
TL;DR: d-Amino acid oxidases are flavor enzymes and have been used in resolution of racemic amino acids and manufacturing of pharmaceuticals, however, the evolved H2O2 during the catalysis has deleterious and inhibitory effects.
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Reticular Nanoscience: Bottom-Up Assembly Nanotechnology.
Jacopo Andreo,Romy Ettlinger,Orysia Zaremba,Quim Peña,Ulrich Lächelt,Roberto Fernández de Luis,Ralph Freund,Stefano Canossa,Evelyn Ploetz,Wei Zhu,Christian S. Diercks,Harald Gröger,Stefan Wuttke +12 more
TL;DR: In this paper , the authors explore the extension of an interdisciplinary reach by surveying the explored and unexplored possibilities that framework nanoparticles can offer, and localize these unique nanosized reticular materials at the juncture between the molecular and the macroscopic worlds, and describe the resulting synthetic and analytical chemistry.
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Development of MOF "Armor-Plated" Phycocyanin and Synergistic Inhibition of Cellular Respiration for Hypoxic Photodynamic Therapy in Patient-Derived Xenograft Models.
Danyang Chen,Danyang Chen,Meng Suo,Meng Suo,Jiancheng Guo,Wenxue Tang,Wei Jiang,Ying Liu,Yanhong Duo +8 more
TL;DR: It is proposed that the “armor‐plating” of protein PS agents with ZIF‐8 in combination with PPV may be a promising approach to precision medicine‐mediated tumor treatment.
Journal ArticleDOI
Silica Capsules Templated from Metal–Organic Frameworks for Enzyme Immobilization and Catalysis
TL;DR: In this article, a facile method to fabricate silica (SiO2) capsules using zeolitic imidazole framework-8 nanoparticles (ZIF-8 NPs) as templates for enzyme immobilization and catalysis is reported.
Journal ArticleDOI
Calix[4]arene tetracarboxylic acid-treated lipase immobilized onto metal-organic framework: Biocatalyst for ester hydrolysis and kinetic resolution
TL;DR: In this article, a zeolitic imidazole framework-8 (ZIF-8) was used for enzyme immobilization for bio-catalysis, and the preconditioned CRL was pretreated with calix [4]arene tetracarboxylic acid (Calix) and reacted with Zn and imidrazole by co-precipitation method.
References
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Journal ArticleDOI
The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
Journal ArticleDOI
Reticular synthesis and the design of new materials
Omar M. Yaghi,Michael O'Keeffe,Nathan W. Ockwig,Hee K. Chae,Hee K. Chae,Mohamed Eddaoudi,Jaheon Kim +6 more
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
Journal ArticleDOI
Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Kyo Sung Park,Zheng Ni,Adrien P. Côté,Jae Yong Choi,Rudan Huang,Fernando J. Uribe-Romo,Hee K. Chae,Michael O'Keeffe,Omar M. Yaghi +8 more
TL;DR: Study of the gas adsorption and thermal and chemical stability of two prototypical members, ZIF-8 and -11, demonstrated their permanent porosity, high thermal stability, and remarkable chemical resistance to boiling alkaline water and organic solvents.
Book ChapterDOI
The assay of catalases and peroxidases.
Britton Chance,A.C. Maehly +1 more
TL;DR: Two methods are described for the catalase assay by disappearance of peroxide are: ultraviolet spectrophotometry and permanganate titration and indirect measurements of the decrease of light absorption caused by the decomposition of hydrogen peroxide byCatalase.
Journal ArticleDOI
Metal-organic frameworks in biomedicine.
Patricia Horcajada,Ruxandra Gref,Tarek Baati,Phoebe K. Allan,Guillaume Maurin,Patrick Couvreur,Gérard Férey,Russell E. Morris,Christian Serre +8 more
TL;DR: Metal Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baati, Phoebe K. Allan, Guillaume Maurin, Patrick Couvreur, G erard F erey, Russell E. Morris, and Christian Serre.