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Isabelle Hoffmann

Researcher at French Institute of Health and Medical Research

Publications -  14
Citations -  332

Isabelle Hoffmann is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 3 publications receiving 239 citations.

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Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

Paul Bastard, +362 more
- 14 Jun 2022 - 
TL;DR: Despite two mRNA vaccine inoculations and the presence of circulating antibodies capable of neutralizing SARS-CoV-2, auto-Abs neutralizing type I IFNs may underlie a significant proportion of hypoxemic COVID-19 pneumonia cases, highlighting the importance of this particularly vulnerable population.
Journal ArticleDOI

Data capture by digital pen in clinical trials: a qualitative and quantitative study.

TL;DR: The digital pen (DP) system has a good acceptability among all investigators in a clinical setting, whether they are experienced with computers or not, and a good accuracy, as compared with double manual data entry.
Journal ArticleDOI

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Daniela Matuozzo, +1273 more
- 05 Apr 2023 - 
TL;DR: In this paper , a genome-wide rare variant burden association analysis in 3269 unvaccinated patients with life-threatening COVID-19, and 1373 un vaccinated SARS-CoV-2-infected individuals without pneumonia was performed.