N
Nancy L. Saccone
Researcher at Washington University in St. Louis
Publications - 133
Citations - 14273
Nancy L. Saccone is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Smoking cessation & Genome-wide association study. The author has an hindex of 46, co-authored 127 publications receiving 13022 citations. Previous affiliations of Nancy L. Saccone include Harvard University.
Papers
More filters
Journal ArticleDOI
The International HapMap Project
John W. Belmont,Paul Hardenbol,Thomas D. Willis,Fuli Yu,Huanming Yang,Lan Yang Ch'Ang,Wei Huang,Bin Liu,Yan Shen,Paul K.H. Tam,Lap-Chee Tsui,Mary M.Y. Waye,Jeffrey Tze Fei Wong,Changqing Zeng,Qingrun Zhang,Mark S. Chee,Luana Galver,Semyon Kruglyak,Sarah S. Murray,Arnold Oliphant,Alexandre Montpetit,Fanny Chagnon,Vincent Ferretti,Martin Leboeuf,Michael S. Phillips,Andrei Verner,Shenghui Duan,Denise L. Lind,Raymond D. Miller,John P. Rice,Nancy L. Saccone,Patricia Taillon-Miller,Ming Xiao,Akihiro Sekine,Koki Sorimachi,Yoichi Tanaka,Tatsuhiko Tsunoda,Eiji Yoshino,David R. Bentley,Sarah E. Hunt,Don Powell,Houcan Zhang,Ichiro Matsuda,Yoshimitsu Fukushima,Darryl Macer,Eiko Suda,Charles N. Rotimi,Clement Adebamowo,Toyin Aniagwu,Patricia A. Marshall,Olayemi Matthew,Chibuzor Nkwodimmah,Charmaine D.M. Royal,Mark Leppert,Missy Dixon,Fiona Cunningham,Ardavan Kanani,Gudmundur A. Thorisson,Peter E. Chen,David J. Cutler,Carl S. Kashuk,Peter Donnelly,Jonathan Marchini,Gilean McVean,Simon Myers,Lon R. Cardon,Andrew P. Morris,Bruce S. Weir,James C. Mullikin,Michael Feolo,Mark J. Daly,Renzong Qiu,Alastair Kent,Georgia M. Dunston,Kazuto Kato,Norio Niikawa,Jessica Watkin,Richard A. Gibbs,Erica Sodergren,George M. Weinstock,Richard K. Wilson,Lucinda Fulton,Jane Rogers,Bruce W. Birren,Hua Han,Hongguang Wang,Martin Godbout,John C. Wallenburg,Paul L'Archevêque,Guy Bellemare,Kazuo Todani,Takashi Fujita,Satoshi Tanaka,Arthur L. Holden,Francis S. Collins,Lisa D. Brooks,Jean E. McEwen,Mark S. Guyer,Elke Jordan,Jane Peterson,Jack Spiegel,Lawrence M. Sung,Lynn F. Zacharia,Karen Kennedy,Michael Dunn,Richard Seabrook,Mark Shillito,Barbara Skene,John Stewart,David Valle,Ellen Wright Clayton,Lynn B. Jorde,Aravinda Chakravarti,Mildred K. Cho,Troy Duster,Troy Duster,Morris W. Foster,Maria Jasperse,Bartha Maria Knoppers,Pui-Yan Kwok,Julio Licinio,Jeffrey C. Long,Pilar N. Ossorio,Vivian Ota Wang,Charles N. Rotimi,Patricia Spallone,Patricia Spallone,Sharon F. Terry,Eric S. Lander,Eric H. Lai,Deborah A. Nickerson,Gonçalo R. Abecasis,David Altshuler,Michael Boehnke,Panos Deloukas,Julie A. Douglas,Stacey Gabriel,Richard R. Hudson,Thomas J. Hudson,Leonid Kruglyak,Yusuke Nakamura,Robert L. Nussbaum,Stephen F. Schaffner,Stephen T. Sherry,Lincoln Stein,Toshihiro Tanaka +145 more
TL;DR: The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance the ability to choose targets for therapeutic intervention.
Journal ArticleDOI
A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci
Ying Liu,Cynthia Helms,Wilson Liao,Lisa C. Zaba,Shenghui Duan,Jennifer M. Gardner,Carol Wise,Andrew Miner,Mary J. Malloy,Clive R. Pullinger,John P. Kane,Scott F. Saccone,Jane Worthington,Ian C Bruce,Pui-Yan Kwok,Alan Menter,James M Krueger,Anne Barton,Nancy L. Saccone,Anne M. Bowcock +19 more
TL;DR: A genome-wide association study was performed to identify genetic factors involved in susceptibility to psoriasis and psoriatic arthritis, inflammatory diseases of the skin and joints in humans, and identified a novel PSA (and potentially PS) locus on chromosome 4q27.
Journal ArticleDOI
Variants in nicotinic receptors and risk for nicotine dependence
Laura J. Bierut,Jerry A. Stitzel,Jen C. Wang,Anthony L. Hinrichs,Richard A. Grucza,Xiaoling Xuei,Nancy L. Saccone,Scott F. Saccone,Sarah Bertelsen,Louis Fox,William J. Horton,Naomi Breslau,John P. Budde,C. Robert Cloninger,Danielle M. Dick,Tatiana Foroud,Dorothy K. Hatsukami,Victor Hesselbrock,Eric O. Johnson,John Kramer,Samuel Kuperman,Pamela A. F. Madden,Kevin Mayo,John I. Nurnberger,Ovide F. Pomerleau,Bernice Porjesz,Oliver Reyes,Marc A. Schuckit,Gary E. Swan,Jay A. Tischfield,Howard J. Edenberg,John P. Rice,Alison Goate +32 more
TL;DR: This study confirms that at least two independent variants in this nicotinic receptor gene cluster contribute to the development of habitual smoking in some populations, and it underscores the importance of multiple genetic variants contributing to theDevelopment of common diseases in various populations.
Journal ArticleDOI
Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability
Laramie E. Duncan,Andrew Ratanatharathorn,Allison E. Aiello,Lynn M. Almli,Amstadter Ab,Allison E. Ashley-Koch,Dewleen G. Baker,Jean C. Beckham,Laura J. Bierut,Jonathan Ian Bisson,Bekh Bradley,Chia-Yen Chen,Shareefa Dalvie,Lindsay A. Farrer,Sandro Galea,Melanie E. Garrett,Joel Gelernter,Guia Guffanti,Michael A. Hauser,Eric O. Johnson,Ronald C. Kessler,Nathan A. Kimbrel,Nathan A. Kimbrel,Anthony P. King,Nastassja Koen,Nastassja Koen,Henry R. Kranzler,Mark W. Logue,Adam X. Maihofer,Alicia R. Martin,Mark W. Miller,Mark W. Miller,Rajendra A. Morey,Nicole R. Nugent,John P. Rice,Stephan Ripke,Stephan Ripke,Stephan Ripke,Andrea L. Roberts,Nancy L. Saccone,Jordan W. Smoller,Jordan W. Smoller,Dan J. Stein,Dan J. Stein,Murray B. Stein,Murray B. Stein,Jennifer A. Sumner,Monica Uddin,Robert J. Ursano,Derek E. Wildman,Rachel Yehuda,Hongyu Zhao,Mark J. Daly,Mark J. Daly,Israel Liberzon,Kerry J. Ressler,Kerry J. Ressler,Caroline M. Nievergelt,Caroline M. Nievergelt,Karestan C. Koenen,Karestan C. Koenen +60 more
TL;DR: The results demonstrate genetic influences on the development of PTSD, identify shared genetic risk between PTSD and other psychiatric disorders and highlight the importance of multiethnic/racial samples.
Journal ArticleDOI
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Caroline M. Nievergelt,Caroline M. Nievergelt,Adam X. Maihofer,Adam X. Maihofer,Torsten Klengel,Torsten Klengel,Elizabeth G. Atkinson,Elizabeth G. Atkinson,Chia-Yen Chen,Chia-Yen Chen,Karmel W. Choi,Karmel W. Choi,Jonathan R. I. Coleman,Shareefa Dalvie,Laramie E. Duncan,Joel Gelernter,Joel Gelernter,Daniel F. Levey,Daniel F. Levey,Mark W. Logue,Renato Polimanti,Renato Polimanti,Allison C. Provost,Andrew Ratanatharathorn,Murray B. Stein,Murray B. Stein,Katy Torres,Katy Torres,Allison E. Aiello,Lynn M. Almli,Ananda B. Amstadter,Søren Bo Andersen,Ole A. Andreassen,Paul A. Arbisi,Allison E. Ashley-Koch,S. Bryn Austin,Esmina Avdibegović,Dragan Babić,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Dewleen G. Baker,Dewleen G. Baker,Jean C. Beckham,Laura J. Bierut,Jonathan Ian Bisson,Marco P. Boks,Elizabeth A. Bolger,Anders D. Børglum,Anders D. Børglum,Bekh Bradley,Megan Brashear,Gerome Breen,Richard A. Bryant,A.C. Bustamante,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Joseph R. Calabrese,José Miguel Caldas de Almeida,Anders M. Dale,Mark J. Daly,Nikolaos P. Daskalakis,Jürgen Deckert,Douglas L. Delahanty,Michelle F. Dennis,Seth G. Disner,Katharina Domschke,Alma Dzubur-Kulenovic,Christopher R. Erbes,Alexandra Evans,Lindsay A. Farrer,Norah C. Feeny,Janine D. Flory,David Forbes,Carol E. Franz,Sandro Galea,Melanie E. Garrett,Bizu Gelaye,Elbert Geuze,Charles F. Gillespie,Aferdita Goci Uka,Scott D. Gordon,Guia Guffanti,Rasha Hammamieh,Supriya Harnal,Michael A. Hauser,Andrew C. Heath,Sian M. J. Hemmings,David M. Hougaard,David M. Hougaard,Miro Jakovljević,Marti Jett,Eric O. Johnson,Ian Jones,Tanja Jovanovic,Xue Jun Qin,Angela G. Junglen,Karen-Inge Karstoft,Milissa L. Kaufman,Ronald C. Kessler,Alaptagin Khan,Nathan A. Kimbrel,Anthony P. King,Nastassja Koen,Henry R. Kranzler,Henry R. Kranzler,William S. Kremen,William S. Kremen,Bruce R. Lawford,Lauren A.M. Lebois,Catrin Lewis,Sarah D. Linnstaedt,Adriana Lori,Bozo Lugonja,Jurjen J. Luykx,Michael J. Lyons,Jessica L. Maples-Keller,Charles R. Marmar,Alicia R. Martin,Alicia R. Martin,Nicholas G. Martin,Douglas Maurer,Matig R. Mavissakalian,Alexander C. McFarlane,Regina E. McGlinchey,Katie A. McLaughlin,Samuel A. McLean,Sarah McLeay,Divya Mehta,William P. Milberg,Mark W. Miller,Rajendra A. Morey,Charles P. Morris,Ole Mors,Ole Mors,Preben Bo Mortensen,Preben Bo Mortensen,Benjamin M. Neale,Benjamin M. Neale,Elliot C. Nelson,Merete Nordentoft,Merete Nordentoft,Sonya B. Norman,Sonya B. Norman,Meaghan O'Donnell,Holly K. Orcutt,Matthew S. Panizzon,Edward S. Peters,Alan L. Peterson,Matthew Peverill,Robert H. Pietrzak,Robert H. Pietrzak,Melissa A. Polusny,John P. Rice,Stephan Ripke,Stephan Ripke,Stephan Ripke,Victoria B. Risbrough,Victoria B. Risbrough,Andrea L. Roberts,Alex O. Rothbaum,Barbara O. Rothbaum,Peter Roy-Byrne,Kenneth J. Ruggiero,Ariane Rung,Bart P. F. Rutten,Nancy L. Saccone,Sixto E. Sanchez,Dick Schijven,Soraya Seedat,Antonia V. Seligowski,Julia S. Seng,Christina M. Sheerin,Derrick Silove,Alicia K. Smith,Jordan W. Smoller,Jordan W. Smoller,Scott R. Sponheim,Dan J. Stein,Jennifer S. Stevens,Jennifer A. Sumner,Martin H. Teicher,Wesley K. Thompson,Edward J. Trapido,Monica Uddin,Robert J. Ursano,Leigh van den Heuvel,Miranda Van Hooff,Eric Vermetten,Christiaan H. Vinkers,Joanne Voisey,Yunpeng Wang,Yunpeng Wang,Zhewu Wang,Zhewu Wang,Thomas Werge,Thomas Werge,Michelle A. Williams,Douglas E. Williamson,Sherry Winternitz,Christiane Wolf,Erika J. Wolf,Jonathan D. Wolff,Rachel Yehuda,Rachel Yehuda,Ross McD. Young,Keith A. Young,Hongyu Zhao,Lori A. Zoellner,Israel Liberzon,Kerry J. Ressler,Kerry J. Ressler,Magali Haas,Karestan C. Koenen,Karestan C. Koenen +213 more
TL;DR: A GWAS from the Psychiatric Genomics Consortium is reported in which two risk loci in European ancestry and one locus in African ancestry individuals are identified and it is found that PTSD is genetically correlated with several other psychiatric traits.