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Nancy L. Saccone

Researcher at Washington University in St. Louis

Publications -  133
Citations -  14273

Nancy L. Saccone is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Smoking cessation & Genome-wide association study. The author has an hindex of 46, co-authored 127 publications receiving 13022 citations. Previous affiliations of Nancy L. Saccone include Harvard University.

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Book ChapterDOI

Model‐Based Methods for Linkage Analysis

John P. Rice, +2 more
- 01 Jan 2008 - 
TL;DR: This work considers the situation for complex disorders where the maximum Lod score statistic shares some of the advantages of the traditional LOD score approach, but is limited by unknown power and the lack of sharing of the primary data needed to optimally combine analytic results.
Posted ContentDOI

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

Melissa A. Munn-Chernoff, +409 more
- 23 Aug 2019 - 
TL;DR: The genetic correlation between AUD and AN was no longer significant after co-varying for MDD loci, and the patterns of association between eating disorder- and substance-use-related phenotypes highlights the potentially complex and Substance-specific relationships between these behaviors.
Journal ArticleDOI

Enhancing discovery of genetic variants for PTSD through integration of quantitative phenotypes and trauma exposure information

Adam X. Maihofer, +238 more
- 01 Sep 2021 - 
TL;DR: In this article, a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information could enhance the discovery power of PTSD genome-wide association studies (GWAS).
Journal ArticleDOI

A Testable Prognostic Model of Nicotine Dependence

Rachel B. Ramoni, +4 more
- 01 Sep 2009 - 
TL;DR: Using Bayesian networks, a multivariate predictive model is generated which has markedly enhanced predictive accuracy on fitted values relative to that of individual SNPs, and promises to shed new light on the common, complex trait nicotine dependence.
Journal ArticleDOI

Are genetic variants for tobacco smoking associated with cannabis involvement

Arpana Agrawal, +11 more
- 01 May 2015 - 
TL;DR: The modest associations between cannabis involvement and SNPs for tobacco smoking were not independent of the comorbidity between tobacco and cannabis involvement, and larger samples of individuals might be required to articulate the specific genetic architecture of cannabis involvement.