Institution
Government College
About: Government College is a based out in . It is known for research contribution in the topics: Population & Ring (chemistry). The organization has 4481 authors who have published 5986 publications receiving 57398 citations.
Papers published on a yearly basis
Papers
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TL;DR: The Ternary systems performed well as a result of comprehensive effect of ternary complexation and particle size reduction achieved by a spray drying technology and the stability constants of binary systems were remarkably improved in presence of ARG, indicating positive effect of its addition.
51 citations
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30 Mar 2012TL;DR: In this article, two identical with same dimensions, experimental set up of flat plate collectors using -heat pipes were fabricated and two identical wickless copper heat pipes were used having length 620 mm and outer diameter of 18 mm.
Abstract: In present study two identical with same dimensions, experimental set up of flat plate collectors using -heat pipes were fabricated. In each set up three identical wickless copper heat pipes are used having length 620 mm and outer diameter of 18 mm. The working fluid used in one set up is pure water and in another pure water with nanoparticles.
50 citations
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50 citations
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Johns Hopkins University1, Umm al-Qura University2, University of Dammam3, Pennsylvania State University4, Al-Azhar University5, Punjab Agricultural University6, Indian Veterinary Research Institute7, Government College8, University of Dhaka9, BGC Trust University Bangladesh10, Islamic University11, University of New South Wales12
TL;DR: In this article, a review explains the interrelationships of hyper-inflammatory response or cytokine storm with organ damage and the disease severity and the authors have thrown light on the diverse mechanisms and risk factors that influence pathogenesis and the molecular pathways that lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and multiple organ damage.
Abstract: The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though preventive vaccines and treatment methods are out on the market, a specific cure for the disease has not been discovered. Recent investigations and research studies primarily focus on the immunopathology of the disease. A healthy immune system responds immediately after viral entry, causing immediate viral annihilation and recovery. However, an impaired immune system causes extensive systemic damage due to an unregulated immune response characterized by the hypersecretion of chemokines and cytokines. The elevated levels of cytokine or hypercytokinemia leads to acute respiratory distress syndrome (ARDS) along with multiple organ damage. Moreover, the immune response against SARS-CoV-2 has been linked with race, gender, and age; hence, this viral infection’s outcome differs among the patients. Many therapeutic strategies focusing on immunomodulation have been tested out to assuage the cytokine storm in patients with severe COVID-19. A thorough understanding of the diverse signaling pathways triggered by the SARS-CoV-2 virus is essential before contemplating relief measures. This present review explains the interrelationships of hyperinflammatory response or cytokine storm with organ damage and the disease severity. Furthermore, we have thrown light on the diverse mechanisms and risk factors that influence pathogenesis and the molecular pathways that lead to severe SARS-CoV-2 infection and multiple organ damage. Recognition of altered pathways of a dysregulated immune system can be a loophole to identify potential target markers. Identifying biomarkers in the dysregulated pathway can aid in better clinical management for patients with severe COVID-19 disease. A special focus has also been given to potent inhibitors of proinflammatory cytokines, immunomodulatory and immunotherapeutic options to ameliorate cytokine storm and inflammatory responses in patients affected with COVID-19.
50 citations
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TL;DR: A series of 2,5-di(4-aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a-j obtained via multistep synthesis from hydroxybenzophenones 4a-e exhibited moderate to good anti-cancer activity.
50 citations
Authors
Showing all 4481 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rajesh Kumar | 149 | 4439 | 140830 |
Sanjeev Kumar | 113 | 1325 | 54386 |
Rakesh Kumar | 91 | 1959 | 39017 |
Praveen Kumar | 88 | 1339 | 35718 |
V. Balasubramanian | 54 | 457 | 10951 |
Ghulam Murtaza | 53 | 1005 | 14516 |
Marimuthu Govindarajan | 52 | 212 | 6738 |
Muhammad Akram | 43 | 393 | 7329 |
Ghulam Abbas | 40 | 439 | 6396 |
Shivaji H. Pawar | 39 | 168 | 4754 |
Muhammad Afzal | 38 | 118 | 4318 |
Deepankar Choudhury | 35 | 199 | 3543 |
Hidayat Hussain | 34 | 316 | 5185 |
Hitesh Panchal | 34 | 152 | 3161 |
Sher Singh Meena | 33 | 187 | 3547 |