Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in normal and glaucomatous eyes
TL;DR: Compared with fixed compensation, mean-based SLP parameters generated with SLP-VCC have greater correlation with visual function and RNFL thickness assessments obtained with OCT.
Journal ArticleDOI
Photoacoustic ocular imaging
Adam de la Zerda,Yannis M. Paulus,Robert Teed,Sunil Bodapati,Yosh Dollberg,Butrus T. Khuri-Yakub,Mark S. Blumenkranz,Darius M. Moshfeghi,Sanjiv S. Gambhir +8 more
TL;DR: A photoacoustic ocular imaging device was developed and demonstrated its utility in imaging the deeper layers of the eye including the retina, choroid, and optic nerve and was able to visualize the blood distribution of an enucleated pig's eye and an eye of a living rabbit.
Journal Article
Repeatability and reproducibility of macular thickness measurements with the Humphrey OCT system.
TL;DR: OCT is a useful tool in the monitoring of patients with conditions that affect macular thickness, even when there is considerable degradation of the OCT signal, and measurements of gap thickness were still shown to be accurate, precise, reproducible, and repeatable.
Journal Article
Intersession repeatability of macular thickness measurements with the Humphrey 2000 OCT
TL;DR: OCT measurements of macular thickness made with the Humphrey 2000 OCT system are repeatable over different sessions with an expected variation of less than 11 microm (99% confidence interval).
References
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