Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
More filters
Journal ArticleDOI
Hyperspectral terahertz microscopy via nonlinear ghost-imaging
Luana Olivieri,Juan Sebastian Totero Gongora,Luke Peters,Vittorio Cecconi,Antonio Cutrona,Jacob Tunesi,Robyn Tucker,Alessia Pasquazi,Marco Peccianti +8 more
TL;DR: In this paper, a time-resolved nonlinear ghost imaging technique based on near-field, optical-to-terahertz nonlinear conversion and detection of illumination patterns is proposed.
Journal ArticleDOI
Fiber-based polarization-sensitive Fourier domain optical coherence tomography using B-scan-oriented polarization modulation method.
Masahiro Yamanari,Shuichi Makita,Violeta Dimitrova Madjarova,Toyohiko Yatagai,Yoshiaki Yasuno +4 more
TL;DR: Fiber-based high-speed polarization-sensitive Fourier domain optical coherence tomography (PS-FD-OCT) is developed at 840 nm wavelength using polarization modulation method and three dimensional phase retardation images show the potentials for applying the system to biological and medical studies.
Journal ArticleDOI
Optical coherence tomography predicts visual outcome for pituitary tumors
Helen V. Danesh-Meyer,Helen V. Danesh-Meyer,Aaron Wong,Taras Papchenko,Kaliopy Matheos,Stanley S. Stylli,Andrew D. Nichols,Andrew D. Nichols,Chris Frampton,Mark Daniell,Peter J. Savino,Andrew H. Kaye,Andrew H. Kaye +12 more
TL;DR: The results indicate that long-term visual recovery after surgical decompression of pituitary lesions is predicted by pre-operative OCT RNFL, and patients with normal RNFL thickness show an increased propensity for visual recovery.
Journal ArticleDOI
Quantitative SD-OCT imaging biomarkers as indicators of age-related macular degeneration progression.
TL;DR: The results demonstrate the potential ability of the model to identify those AMD patients at risk of progressing to exudative AMD from an early or intermediate stage.
Journal ArticleDOI
Peripapillary Retinal Nerve Fiber Layer Thickness in a Population of 6-Year-Old Children: Findings by Optical Coherence Tomography
TL;DR: In this article, the distribution of retinal nerve fiber layer (RNFL) thickness by ocular and demographic variables in a population-based study of young children was studied, and the average thickness of RNFL was found to vary significantly with gender, ethnicity, axial length, and refraction.
References
More filters
Journal ArticleDOI
Computerized transverse axial scanning (tomography): Part I. Description of system. 1973.
TL;DR: A technique in which X-ray transmission readings are taken through the head at a multitude of angles: from these data, absorption values of the material contained within the head are calculated on a computer and presented as a series of pictures of slices of the cranium.
Journal ArticleDOI
Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss.
Alfred Sommer,Joanne Katz,Harry A. Quigley,Neil R. Miller,Alan L. Robin,Ronald C. Richter,Kathe A. Witt +6 more
TL;DR: Nerve fiber layer defects expanded with time, often by the development and coalescence of adjacent areas of damage, and field defects closely corresponded, but nerve fiber layer loss was generally more widespread.
Journal ArticleDOI
Theory and practice of scanning optical microscopy
Tony Wilson,Colin J. R. Sheppard +1 more
Journal ArticleDOI
Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma.
TL;DR: Estimates suggest that visual field sensitivity in automated testing begins to decline soon after the initial loss of ganglion cells in human eyes with glaucoma, and that this decline is most pronounced in areas that had 0-dB sensitivity in the field test.