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Optical coherence tomography

TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Abstract
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.

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Patent

Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands

TL;DR: In this paper, a method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (LCI) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies, is presented.
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Intravitreal triamcinolone for uveitic cystoid macular edema: an optical coherence tomography study.

TL;DR: Complete anatomic and, to some extent, functional recovery can be induced by intravitreal TA despite long-term refractory inflammatory CME, and optical coherence tomography aids in the management of these cases.
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Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s.

TL;DR: Buffered Fourier domain mode locking (FDML), a technique for tailoring the output and multiplying the sweep rate of FDML lasers, is described and the role of the laser source in dynamic range versus sensitivity performance in optical coherence tomography (OCT) imaging is investigated.
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ReLayNet: retinal layer and fluid segmentation of macular optical coherence tomography using fully convolutional networks.

TL;DR: A new fully convolutional deep architecture, termed ReLayNet, is proposed for end-to-end segmentation of retinal layers and fluid masses in eye OCT scans, validated on a publicly available benchmark dataset with comparisons against five state-of-the-art segmentation methods.
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High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography☆☆☆

TL;DR: In this paper, the ability of optical coherence tomography to provide detailed images of subsurface structures in the upper gastrointestinal (GI) tract was investigated and the diagnostic information provided by this new imaging modality suggests that it may be a useful adjunct to endoscopy.
References
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Journal ArticleDOI

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TL;DR: A technique in which X-ray transmission readings are taken through the head at a multitude of angles: from these data, absorption values of the material contained within the head are calculated on a computer and presented as a series of pictures of slices of the cranium.
Journal ArticleDOI

Clinically detectable nerve fiber atrophy precedes the onset of glaucomatous field loss.

TL;DR: Nerve fiber layer defects expanded with time, often by the development and coalescence of adjacent areas of damage, and field defects closely corresponded, but nerve fiber layer loss was generally more widespread.
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Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma.

TL;DR: Estimates suggest that visual field sensitivity in automated testing begins to decline soon after the initial loss of ganglion cells in human eyes with glaucoma, and that this decline is most pronounced in areas that had 0-dB sensitivity in the field test.
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