Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Journal ArticleDOI
Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning.
John N. Ratchford,Shiv Saidha,Elias S. Sotirchos,Jiwon Oh,Michaela A. Seigo,Christopher Eckstein,Christopher Eckstein,Mary K Durbin,Jonathan D. Oakley,Scott A. Meyer,Amy Conger,Teresa C. Frohman,Scott D. Newsome,Laura J. Balcer,Elliot M. Frohman,Peter A. Calabresi +15 more
TL;DR: The findings suggest that retinal changes in MS reflect global CNS processes, and that OCT-derived GCIP thickness measures may have utility as an outcome measure for assessing neuroprotective agents, particularly in early, active MS.
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Central corneal thickness determined with optical coherence tomography in various types of glaucoma
Martin Bechmann,Martin Thiel,Bernhard Roesen,Stephanie Ullrich,Michael W. Ulbig,Klaus Ludwig +5 more
TL;DR: The need for a combined measurement of IOP and CCT in order to obtain exact IOP readings is emphasised, because of thinner C CT in patients with LTG, PEX, and POAG this may result in underestimation of Iop, whereas thicker corneas may lead to an overestimated IOP in subjects with OH.
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Comparison of PDE-Based Nonlinear Diffusion Approaches for Image Enhancement and Denoising in Optical Coherence Tomography
H.M. Salinas,D.C. Fernandez +1 more
TL;DR: The numerical values of the image quality metrics along with the qualitative analysis results indicated the good feature preservation performance of the complex diffusion process, as desired for better diagnosis in medical imaging processing.
Journal ArticleDOI
Cystoid macular edema.
Tryfon Rotsos,Marilita M Moschos +1 more
TL;DR: The goal of this paper is to review the current status of this treatment for macular edema due to diabetic maculopathy, central retinal vein occlusion and post-cataract surgery and the results of recent multicenter clinical trials are quoted.
Journal ArticleDOI
Fast Acquisition and Reconstruction of Optical Coherence Tomography Images via Sparse Representation
Leyuan Fang,Shutao Li,Ryan P. McNabb,Qing Nie,Anthony N. Kuo,Cynthia A. Toth,Joseph A. Izatt,Sina Farsiu +7 more
TL;DR: This novel image restoration method, which is a major improvement and generalization of the multi-scale sparsity based tomographic denoising (MSBTD) algorithm, utilizes sparse representation dictionaries constructed from previously collected datasets and qualitatively and quantitatively outperforms other state-of-the-art methods.
References
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