Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Assessment of coronary plaque collagen with polarization sensitive optical coherence tomography (PS-OCT)
Susanne D. Giattina,Brian K. Courtney,Paul R. Herz,Michelle Harman,Sonya Shortkroff,Sonya Shortkroff,Debra L. Stamper,Debra L. Stamper,Bin Liu,Bin Liu,James G. Fujimoto,Mark E. Brezinski,Mark E. Brezinski +12 more
TL;DR: The capability of PS-OCT to assess plaque collagen content, in addition to its ability to generate high resolution structural assessments, make it a potentially powerful technology for identifying high risk plaques.
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A two-axis electrothermal micromirror for endoscopic optical coherence tomography
TL;DR: In this paper, a 1-mm/sup 2/2/2 2/3/2-axis, single-crystalline-silicon (SCS)-based aluminum-coated scanning micromirror with large rotation angle (up to 40/spl deg/), which can be used in an endoscopic optical coherence tomography imaging system is presented.
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Dynamic light scattering optical coherence tomography
TL;DR: An integration of dynamic light scattering (DLS) and optical coherence tomography (OCT) for high-resolution 3D imaging of heterogeneous diffusion and flow is introduced and a fitting algorithm is developed to estimate dynamic parameters including the axial and transverse velocities and the diffusion coefficient.
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Investigation of the mesoscale structure and volumetric features of biofilms using optical coherence tomography
TL;DR: It is shown that CLSM images do not necessarily provide an accurate representation of the biofilm structure at the mesoscale, and the typical characteristic parameters obtained from CLSM image stacks differ largely from those calculated from OCT images.
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Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography
Jong S. Kim,Hiroshi Ishikawa,Kyung Rim Sung,Juan A Xu,Gadi Wollstein,Richard A. Bilonick,Michelle L. Gabriele,Larry Kagemann,Jay S. Duker,James G. Fujimoto,Joel S. Schuman +10 more
TL;DR: SD-OCT 3D cube data generally showed better RNFL measurement reproducibility than TD-O CT, and two methods defining the optic nerve head (ONH) centring: Centred Each Time (CET) vs Centred Once (CO), in terms of RNFL thickness measurement variability on SD- OCT.
References
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