Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Technology Insight: laser-scanning confocal microscopy and endocytoscopy for cellular observation of the gastrointestinal tract
TL;DR: Novel imaging technologies may make in vivo histological diagnosis by virtual histology possible for early-stage cancer and its precursors in the gastrointestinal tract.
Journal ArticleDOI
Object classification through scattering media with deep learning on time resolved measurement
TL;DR: This work uses a data driven approach and leverage convolutional neural networks to learn a model that is invariant to calibration parameters variations within the training range and nearly invariant beyond that, which effectively allows robust imaging through scattering conditions that is not sensitive to calibration.
Journal ArticleDOI
Ultrahigh resolution real time OCT imaging using a compact femtosecond Nd:Glass laser and nonlinear fiber
Stephane Bourquin,Aaron D. Aguirre,Ingmar Hartl,Pei-Lin Hsiung,Tony H. Ko,James G. Fujimoto,Tim A. Birks,William J. Wadsworth,U. Bünting,Daniel Kopf +9 more
TL;DR: In vivo, ultrahigh resolution, real time OCT imaging is demonstrated using a compact femtosecond Nd:Glass laser that is spectrally broadened in a high numerical aperture single mode fiber that enables broad bandwidth, high-speed group delay scanning.
Journal ArticleDOI
Combining structural and functional testing for detection of glaucoma.
Neha Shah,Christopher Bowd,Felipe A. Medeiros,Robert N. Weinreb,Pamela A. Sample,Esther M. Hoffmann,Linda M. Zangwill +6 more
TL;DR: A combination of parameters from structural tests and functional tests can improve the sensitivity of glaucoma detection.
Posted Content
Intra-Retinal Layer Segmentation of 3D Optical Coherence Tomography Using Coarse Grained Diffusion Map
TL;DR: In this paper, a fast segmentation method based on a new variant of spectral graph theory named diffusion maps was proposed for OCT images depicting macular and optic nerve head appearance, which does not require edge-based image information and relies on regional image texture.
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