Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Advances in the microrheology of complex fluids.
TL;DR: The requirements for a simple modern particle tracking microrheology experiment are introduced, the error analysis methods associated with it and the mathematical techniques required to calculate the linear viscoelasticity are discussed.
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Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management
Samir K. Ballas,Muge R. Kesen,Morton F. Goldberg,Gerard A. Lutty,Carlton Dampier,Ifeyinwa Osunkwo,Winfred C. Wang,Carolyn Hoppe,Ward Hagar,Deepika S. Darbari,Punam Malik +10 more
TL;DR: The aim of this paper is to review available current approaches to manage the major complications of sickle cell disease and hope that this will establish another preliminary forum among providers that may eventually lead the way to better outcomes.
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Linear birefringence of the central human cornea.
TL;DR: The variation of corneal birefringence among individuals is substantial enough to produce large, uncontrolled differences in the polarization state of a measuring beam, differences that can introduce variability in newer technologies for ophthalmic diagnosis.
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Measurement of the refractive index of human teeth by optical coherence tomography
TL;DR: A novel method based on optical coherence tomography (OCT) for the accurate measurement of the refractive index of in vitro human teeth that has great potential for the clinical diagnosis of early dental caries.
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Ultrahigh resolution optical coherence tomography imaging with a broadband superluminescent diode light source
Tony H. Ko,Desmond C. Adler,James G. Fujimoto,Dmitry Mamedov,Viatcheslav V. Prokhorov,Vladimir R. Shidlovski,S D Yakubovich +6 more
TL;DR: These results demonstrate that it is possible to perform in vivo in vivo ultrahigh resolution optical coherence tomography imaging using a superluminescent diode light source that is inexpensive, compact, and easy to operate.
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