Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TLDR
OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.Abstract:
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.read more
Citations
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Patent
Methods and apparatus for high-speed longitudinal scanning in imaging systems
TL;DR: In this article, an imaging system (2) consisting of a sample (25) and a rotating element (175) is calibrated to the system, and a scan analyzer and correction unit (160) uses the system calibration information along with synchronization information to correct for return signal degradation or errors due to imperfections in the rotating element.
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Vascular Endothelial Growth Factor Is a Critical Stimulus for Diabetic Macular Edema
Quan Dong Nguyen,S. Tatlipinar,Syed Mahmood Shah,Julia A. Haller,Edward Quinlan,Jennifer U. Sung,Ingrid Zimmer-Galler,Diana V. Do,Peter A. Campochiaro +8 more
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Endoscopic optical coherence tomography based on a microelectromechanical mirror.
TL;DR: An endoscopic optical coherence tomography system based on a microelectromechanical mirror to facilitate lateral light scanning is described and applications in thickness measurement and bladder tissue imaging are demonstrated.
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The retinal nerve fiber layer thickness in ocular hypertensive, normal, and glaucomatous eyes with optical coherence tomography.
TL;DR: Retinal nerve fiber layer was significantly thinner in glaucomatous eyes than in ocular hypertensive and normal eyes throughout 360 degrees and in all quadrants.
References
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