Journal ArticleDOI
The economic cost of brain disorders in Europe
TLDR
This new report presents updated, more accurate, and comprehensive 2010 estimates of annual costs for brain disorders in Europe for 30 European countries.Abstract:
BACKGROUND AND PURPOSE: In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, ...read more
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Current and future noise impacts of the UK hub airport
TL;DR: In this article, the authors modeled the present day noise impacts from two London airports: Heathrow and Gatwick, and found that noise generated by operations at these two airports impacts 255,800 people, contributing to 54 myocardial infarctions and 17 premature mortalities each year.
Journal ArticleDOI
Long-term cost-effectiveness of cognitive behavioral therapy versus psychodynamic therapy in social anxiety disorder.
Nina Egger,Alexander Konnopka,Manfred E. Beutel,Stephan Herpertz,Wolfgang Hiller,Juergen Hoyer,Simone Salzer,Ulrich Stangier,Bernhard Strauss,Ulrike Willutzki,Joerg Wiltink,Eric Leibing,Falk Leichsenring,Hans-Helmut König +13 more
TL;DR: To determine the cost‐effectiveness of cognitive behavioral therapy (CBT) versus psychodynamic therapy (PDT) in the treatment of social anxiety disorder after a follow‐up of 30 months from a societal perspective, a cost-effectiveness study is conducted.
Journal ArticleDOI
Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies.
TL;DR: The use of genome editing, in particular CRISPR-Cas9 technology, has extended the potential of iPSCs, generating new models for a number of disorders, including Alzheimers and Parkinson Disease.
Journal ArticleDOI
Argon attenuates the emergence of secondary injury after traumatic brain injury within a 2-hour incubation period compared to desflurane: an in vitro study.
Linda Grüßer,Rosmarie Blaumeiser-Debarry,Matthias Krings,Benedikt Kremer,Anke Höllig,Rolf Rossaint,Mark Coburn +6 more
TL;DR: It is demonstrated that within a 2-hour incubation time neither argon nor desflurane could affect propidium iodide-detectable cell death in an in vitro TBI model in comparison to the standard atmosphere, although cell death was less with argon 50% than with desflorane 6%.
Journal ArticleDOI
Healthcare use and costs associated with children’s behavior problems
Gabriele Kohlboeck,Gabriele Kohlboeck,Marcel Romanos,Christina M. Teuner,Rolf Holle,Carla M. T. Tiesler,Barbara Hoffmann,Beate Schaaf,Irina Lehmann,Olf Herbarth,Sibylle Koletzko,Carl-Peter Bauer,Andrea von Berg,Dietrich Berdel,Joachim Heinrich +14 more
TL;DR: Investigation of associations between severity of behavior problems, specific symptom domains with healthcare use and costs in school-aged children in Germany found children with emotional symptoms showed highest costs for physicians, psychotherapist, and hospitalization as well as total direct medical costs.
References
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Journal ArticleDOI
The size and burden of mental disorders and other disorders of the brain in Europe 2010
Hans-Ulrich Wittchen,Frank Jacobi,Jürgen Rehm,Jürgen Rehm,Anders Gustavsson,Mikael Svensson,Bengt Jönsson,Jes Olesen,Christer Allgulander,Jordi Alonso,Carlo Faravelli,Laura Fratiglioni,Poul Jennum,Roselind Lieb,Andreas Maercker,J. van Os,Martin Preisig,Luis Salvador-Carulla,Roland Simon,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen +21 more
TL;DR: The true size and burden of disorders of the brain in the EU was significantly underestimated in the past, and Concerted priority action is needed at all levels, including substantially increased funding for basic, clinical and public health research and policy decisions.
Journal ArticleDOI
Cost of disorders of the brain in Europe 2010
Anders Gustavsson,Mikael Svensson,Frank Jacobi,Christer Allgulander,Jordi Alonso,Ettore Beghi,R. Dodel,Mattias Ekman,Carlo Faravelli,Laura Fratiglioni,Brenda Gannon,David P.H. Jones,Poul Jennum,Albena Jordanova,Linus Jönsson,Korinna Karampampa,Martin Knapp,Martin Knapp,Gisela Kobelt,Tobias Kurth,Roselind Lieb,Mattias Linde,Christina Ljungcrantz,Andreas Maercker,Beatrice Melin,Massimo Moscarelli,Amir Musayev,Fiona Norwood,Martin Preisig,Maura Pugliatti,Juergen Rehm,Luis Salvador-Carulla,Brigitte Schlehofer,Roland Simon,Hans-Christoph Steinhausen,Lars Jacob Stovner,Jean-Michel Vallat,Peter Van den Bergh,Jim van Os,Jim van Os,Pieter E. Vos,Weili Xu,Hans-Ulrich Wittchen,Bengt Jönsson,Jes Olesen +44 more
TL;DR: The present report presents much improved cost estimates for the total cost of disorders of the brain in Europe in 2010, covering 19 major groups of disorders, 7 more than previously, of an increased range of age groups and more cost items.
Journal ArticleDOI
Cost of disorders of the brain in Europe.
TL;DR: This paper presents a meta-anatomy of the immune system and its role in disease and injury in the context of clinical practice and shows clear patterns of decline in the aged and disabled.
Journal ArticleDOI
Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents
TL;DR: Although some children are being diagnosed as having ADHD with insufficient evaluation and in some cases stimulant medication is prescribed when treatment alternatives exist, there is little evidence of widespread overdiagnosis or misdiagnosis of ADHD or ofidespread overprescription of methylphenidate by physicians.
Journal ArticleDOI
Revealing the cost of Type II diabetes in Europe.
TL;DR: Current comprehensive economic data on the costs of diabetes are required for policy decisions to optimise resource allocation and to evaluate different approaches for disease management, especially in developing countries.
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