Journal ArticleDOI
The economic cost of brain disorders in Europe
TLDR
This new report presents updated, more accurate, and comprehensive 2010 estimates of annual costs for brain disorders in Europe for 30 European countries.Abstract:
BACKGROUND AND PURPOSE: In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, ...read more
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The Microbiota-Gut-Brain Axis
John F. Cryan,Kenneth J. O’Riordan,Caitlin S. M. Cowan,Kiran V. Sandhu,Thomaz F.S. Bastiaanssen,Marcus Boehme,Martín Gabriel Codagnone,Sofia Cussotto,Christine Fülling,Anna V. Golubeva,Katherine E. Guzzetta,Minal Jaggar,Caitriona M. Long-Smith,Joshua M. Lyte,Jason A. Martin,Alicia Molinero-Perez,Gerard M. Moloney,Emanuela Morelli,Enrique Morillas,Rory C. O'Connor,Joana S Cruz-Pereira,Veronica L. Peterson,Kieran Rea,Nathaniel L. Ritz,Eoin Sherwin,Simon Spichak,Emily M. Teichman,Marcel van de Wouw,Ana Paula Ventura-Silva,Shauna E. Wallace-Fitzsimons,Niall P. Hyland,Gerard Clarke,Timothy G. Dinan +32 more
TL;DR: Future studies will focus on understanding the mechanisms underlying the microbiota-gut-brain axis and attempt to elucidate microbial-based intervention and therapeutic strategies for neuropsychiatric disorders.
Journal ArticleDOI
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Andrew I R Maas,David K. Menon,P. David Adelson,Nada Andelic,Michael J. Bell,Antonio Belli,Peter Bragge,Alexandra Brazinova,Andras Buki,Randall M. Chesnut,Giuseppe Citerio,Mark Coburn,D. Jamie Cooper,A Tamara Crowder,Endre Czeiter,Marek Czosnyka,Ramon Diaz-Arrastia,Jens P. Dreier,Ann-Christine Duhaime,Ari Ercole,Thomas A. van Essen,Valery L. Feigin,Guoyi Gao,Joseph T. Giacino,Laura E. Gonzalez-Lara,Russell L. Gruen,Russell L. Gruen,Deepak Gupta,Jed A. Hartings,Sean Hill,Jiyao Jiang,Naomi Ketharanathan,Erwin J. O. Kompanje,Linda Lanyon,Steven Laureys,Fiona Lecky,Harvey S. Levin,Hester F. Lingsma,Marc Maegele,Marek Majdan,Geoffrey T. Manley,Jill A. Marsteller,Luciana Mascia,Charles McFadyen,Stefania Mondello,Virginia F. J. Newcombe,Aarno Palotie,Aarno Palotie,Aarno Palotie,Paul M. Parizel,Wilco C. Peul,James Piercy,Suzanne Polinder,Louis Puybasset,Todd E. Rasmussen,Rolf Rossaint,Peter Smielewski,Jeannette Söderberg,Simon J. Stanworth,Murray B. Stein,Nicole von Steinbüchel,William Stewart,Ewout W. Steyerberg,Ewout W. Steyerberg,Nino Stocchetti,Anneliese Synnot,Anneliese Synnot,Braden Te Ao,Olli Tenovuo,Alice Theadom,Dick Tibboel,Walter Videtta,Kevin K.W. Wang,W. Huw Williams,Lindsay Wilson,Kristine Yaffe,Hadie Adams,Vanni Agnoletti,Judith Allanson,Krisztina Amrein,Norberto Andaluz,Audny Anke,Anna Antoni,Arjan Bastiaan van As,Gérard Audibert,Antun Azaševac,Philippe Azouvi,Maria Luisa Azzolini,Camelia Baciu,Rafael Badenes,Karen M. Barlow,Ronald H. M. A. Bartels,Ursula Bauerfeind,Miriam H. Beauchamp,Darcy Beer,Ronny Beer,Francisco Javier Belda,Bo-Michael Bellander,Rémy Bellier,Habib Benali,Thierry Benard,Valzerda Beqiri,Luigi Beretta,Francis Bernard,Guido Bertolini,Federico Bilotta,Morten Blaabjerg,Hugo den Boogert,Kathy Boutis,Pierre Bouzat,Brian L. Brooks,Camilla Brorsson,Monika Bullinger,Emma Burns,Calappi E,Peter Cameron,Elsa Carise,Ana M. Castaño-Leon,Francesco Causin,Giorgio Chevallard,Arturo Chieregato,Brian R. Christie,Maryse C. Cnossen,Jonathan P. Coles,Johnny Collett,Francesco Della Corte,William Craig,Gábor Csató,Ákos Csomós,Nicola Curry,Claire Dahyot-Fizelier,Helen Dawes,Carol DeMatteo,Bart Depreitere,Deborah Dewey,Jeroen T. J. M. van Dijck,Đula Đilvesi,Diederik W.J. Dippel,Kemal Dizdarevic,Emma Donoghue,Or Duek,Guy-Loup Dulière,Adelaida Dzeko,George A. Eapen,Carolyn A. Emery,Shane W. English,Patrick Esser,Erzsébet Ezer,Martin Fabricius,Junfeng Feng,Dean Fergusson,Anthony Figaji,Joanne Fleming,Kelly A Foks,G. Francony,Stephen B. Freedman,Ulderico Freo,Shirin Frisvold,Isabelle Gagnon,Damien Galanaud,Dashiell Gantner,Benoit Giraud,Ben Glocker,Jagos Golubovic,Pedro A Gómez López,Wayne A. Gordon,Primoz Gradisek,Jocelyn Gravel,Donald E. G. Griesdale,Francesca Grossi,Juanita A. Haagsma,Asta Håberg,Iain K. Haitsma,Wim Van Hecke,Raimund Helbok,Eirik Helseth,Caroline M. van Heugten,Cornelia W. E. Hoedemaekers,Stefan Höfer,Lindsay Horton,Jiyuan Hui,Jilske A Huijben,Peter J. Hutchinson,Bram Jacobs,Mathieu van der Jagt,Stefan Jankowski,Koen Janssens,Bojan Jelaca,Kelly Jones,Konstantinos Kamnitsas,Rafael Kaps,Mladen Karan,Ari Katila,Kirsi-Maija Kaukonen,Véronique De Keyser,Riku Kivisaari,Angelos G. Kolias,Balint Kolumban,Ksenija Kolundžija,Daniel Kondziella,Lars-Owe D. Koskinen,Noémi Kovács,Andreas H. Kramer,Demitri Kutsogiannis,Theodoros Kyprianou,Alfonso Lagares,Francois Lamontagne,Roberto Latini,François Lauzier,Isaac Lazar,Christian Ledig,Rolf Lefering,Valerie Legrand,Leon Levi,Roger Lightfoot,Angels Lozano,Stephen MacDonald,Sebastian Major,Alex Manara,Pauline Manhes,Hugues Maréchal,Costanza Martino,Alessandro Masala,Serge Masson,Julia Mattern,Bradford J. McFadyen,Catherine McMahon,Maureen O. Meade,Béla Melegh,Tomas Menovsky,Lynne Moore,Marta M Correia,Maria Cristina Morganti-Kossmann,Holger Muehlan,Pratik Mukherjee,Lynnette Murray,Joukje van der Naalt,Ancuta Negru,David W. Nelson,Daan Nieboer,Quentin Noirhomme,József Nyirádi,Mauro Oddo,David O. Okonkwo,Annemarie W. Oldenbeuving,Fabrizio Ortolano,Martin H. Osmond,Jean-François Payen,Vincent Perlbarg,Paolo Persona,Nicolas Pichon,Anna Piippo-Karjalainen,Sebastien Pili-Floury,Matti Pirinen,Horia Ple,Maria A. Poca,Jussi P. Posti,Dominique Van Praag,Alain Ptito,Andreea Radoi,Arminas Ragauskas,Arminas Ragauskas,Rahul Raj,Ruben G. L. Real,Nick Reed,Jonathan Rhodes,Claudia S. Robertson,Saulius Rocka,Saulius Rocka,Cecilie Røe,Olav Røise,Gerwin Roks,Jonathan Rosand,Jeffrey V. Rosenfeld,Christina Rosenlund,Guy Rosenthal,Sandra Rossi,Daniel Rueckert,Godard C.W. de Ruiter,Marco Sacchi,Barbara J. Sahakian,Juan Sahuquillo,Oliver W. Sakowitz,Gerardo Salvato,Renán Sánchez-Porras,János Sándor,Grinder Sangha,Nadine Schäfer,Silke Schmidt,Kathryn J Schneider,David M. Schnyer,Herbert Schöhl,Guus G. Schoonman,Rico Frederik Schou,Özcan Sir,Toril Skandsen,Dirk Smeets,Abayomi Sorinola,Emmanuel Stamatakis,Ana Stevanovic,Robert Stevens,Nina Sundström,Fabio Silvio Taccone,Fabio Silvio Taccone,Riikka S.K. Takala,Päivi Tanskanen,Mark Taylor,Ralph Telgmann,Nancy R. Temkin,Guido Teodorani,Matthew Thomas,Christos M. Tolias,Tony Trapani,Alexis F. Turgeon,Peter Vajkoczy,Alex B. Valadka,Egils Valeinis,Shirley Vallance,Zoltan Vamos,Alessia Vargiolu,Emmanuel Vega,Jan Verheyden,Anne Vik,Rimantas Vilcinis,Carmen L.A. Vleggeert-Lankamp,Lidia Vogt,Victor Volovici,Daphne C. Voormolen,Peter Vulekovic,Thijs Vande Vyvere,Julia Van Waesberghe,Lars Wessels,Eno Wildschut,Guy B. Williams,Maren K.L. Winkler,Stefan Wolf,Gordon Wood,Nektaria Xirouchaki,Alexander Younsi,Menashe Zaaroor,Veronika Zelinkova,Roger Zemek,Fabrizio Zumbo +342 more
TL;DR: The InTBIR Participants and Investigators have provided informed consent for the study to take place in Poland.
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Short- and long-term health consequences of sleep disruption.
TL;DR: The potential consequences of sleep disruption should be cognizant of how managing underlying medical conditions may help to optimize sleep continuity and consider prescribing interventions that minimize sleep disruption.
Journal ArticleDOI
A review of depression and suicide risk assessment using speech analysis
Nicholas Cummins,Stefan Scherer,Jarek Krajewski,Sebastian Schnieder,Julien Epps,Thomas F. Quatieri +5 more
TL;DR: How common paralinguistic speech characteristics are affected by depression and suicidality and the application of this information in classification and prediction systems is reviewed.
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Pathophysiology of Migraine
TL;DR: This review focuses on emerging concepts that drive the science of migraine in both a mechanistic direction and a therapeutic direction.
References
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Journal ArticleDOI
The size and burden of mental disorders and other disorders of the brain in Europe 2010
Hans-Ulrich Wittchen,Frank Jacobi,Jürgen Rehm,Jürgen Rehm,Anders Gustavsson,Mikael Svensson,Bengt Jönsson,Jes Olesen,Christer Allgulander,Jordi Alonso,Carlo Faravelli,Laura Fratiglioni,Poul Jennum,Roselind Lieb,Andreas Maercker,J. van Os,Martin Preisig,Luis Salvador-Carulla,Roland Simon,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen +21 more
TL;DR: The true size and burden of disorders of the brain in the EU was significantly underestimated in the past, and Concerted priority action is needed at all levels, including substantially increased funding for basic, clinical and public health research and policy decisions.
Journal ArticleDOI
Cost of disorders of the brain in Europe 2010
Anders Gustavsson,Mikael Svensson,Frank Jacobi,Christer Allgulander,Jordi Alonso,Ettore Beghi,R. Dodel,Mattias Ekman,Carlo Faravelli,Laura Fratiglioni,Brenda Gannon,David P.H. Jones,Poul Jennum,Albena Jordanova,Linus Jönsson,Korinna Karampampa,Martin Knapp,Martin Knapp,Gisela Kobelt,Tobias Kurth,Roselind Lieb,Mattias Linde,Christina Ljungcrantz,Andreas Maercker,Beatrice Melin,Massimo Moscarelli,Amir Musayev,Fiona Norwood,Martin Preisig,Maura Pugliatti,Juergen Rehm,Luis Salvador-Carulla,Brigitte Schlehofer,Roland Simon,Hans-Christoph Steinhausen,Lars Jacob Stovner,Jean-Michel Vallat,Peter Van den Bergh,Jim van Os,Jim van Os,Pieter E. Vos,Weili Xu,Hans-Ulrich Wittchen,Bengt Jönsson,Jes Olesen +44 more
TL;DR: The present report presents much improved cost estimates for the total cost of disorders of the brain in Europe in 2010, covering 19 major groups of disorders, 7 more than previously, of an increased range of age groups and more cost items.
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Cost of disorders of the brain in Europe.
TL;DR: This paper presents a meta-anatomy of the immune system and its role in disease and injury in the context of clinical practice and shows clear patterns of decline in the aged and disabled.
Journal ArticleDOI
Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents
TL;DR: Although some children are being diagnosed as having ADHD with insufficient evaluation and in some cases stimulant medication is prescribed when treatment alternatives exist, there is little evidence of widespread overdiagnosis or misdiagnosis of ADHD or ofidespread overprescription of methylphenidate by physicians.
Journal ArticleDOI
Revealing the cost of Type II diabetes in Europe.
TL;DR: Current comprehensive economic data on the costs of diabetes are required for policy decisions to optimise resource allocation and to evaluate different approaches for disease management, especially in developing countries.
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Samy,Juan Sanabria,Juan Sanabria,Damian Santomauro,Itamar S. Santos,João Vasco Santos,Milena M Santric Milicevic,Benn Sartorius,Maheswar Satpathy,Monika Sawhney,Sonia Saxena,Maria Inês Schmidt,Ione Jayce Ceola Schneider,Ben Schöttker,David C. Schwebel,Falk Schwendicke,Soraya Seedat,Sadaf G. Sepanlou,Sadaf G. Sepanlou,Edson Serván-Mori,Tesfaye Setegn,Katya Anne Shackelford,Amira Shaheen,Masood Ali Shaikh,Mansour Shamsipour,Sheikh Mohammed Shariful Islam,Sheikh Mohammed Shariful Islam,Jayendra Sharma,Rajesh Sharma,Jun She,Peilin Shi,Chloe Shields,Girma Temam Shifa,Mika Shigematsu,Yukito Shinohara,Rahman Shiri,Reza Shirkoohi,Shreya Shirude,Kawkab Shishani,Mark G. Shrime,Abla M. Sibai,Inga Dora Sigfusdottir,Inga Dora Sigfusdottir,Diego Augusto Santos Silva,João Pedro Silva,Dayane Gabriele Alves Silveira,Jasvinder A. Singh,Narinder Pal Singh,Dhirendra N Sinha,Eirini Skiadaresi,Vegard Skirbekk,Erica Leigh Slepak,Amber Sligar,David L. Smith,Mari Smith,Badr Hasan Sobaih,Eugene Sobngwi,Reed J D Sorensen,Tatiane Cristina Moraes Sousa,Luciano A. Sposato,Chandrashekhar T Sreeramareddy,Vinay Srinivasan,Jeffrey D. Stanaway,Vasiliki Stathopoulou,Nicholas Steel,Murray B. Stein,Dan J. Stein,Dan J. Stein,Timothy J. Steiner,Timothy J. Steiner,Caitlyn Steiner,S. Steinke,S. Steinke,Mark A. Stokes,Lars Jacob Stovner,Bryan Strub,Michelle L Subart,Mu'awiyyah Babale Sufiyan,Bruno F. Sunguya,Bruno F. Sunguya,Patrick J Sur,Patrick J Sur,Soumya Swaminathan,Bryan L. Sykes,Dillon O Sylte,Rafael Tabarés-Seisdedos,Getachew Redae Taffere,Jukka Takala,Nikhil Tandon,Mohammad Tavakkoli,Nuno Taveira,Hugh R. Taylor,Arash Tehrani-Banihashemi,Tesfalidet Tekelab,Abdullah Sulieman Terkawi,Dawit Jember Tesfaye,Belay Tesssema,Ornwipa Thamsuwan,Katie E Thomas,Amanda G. Thrift,Tenaw Yimer Tiruye,Ruoyan Tobe-Gai,Mette Christophersen Tollånes,Mette Christophersen Tollånes,Marcello Tonelli,Roman Topor-Madry,Roman Topor-Madry,Miguel Tortajada,Mathilde Touvier,Bach Xuan Tran,Suryakant Tripathi,Christopher Troeger,Thomas Truelsen,Derrick Tsoi,Kald Beshir Tuem,Emin Murat Tuzcu,Stefanos Tyrovolas,Kingsley N. Ukwaja,Eduardo A. Undurraga,Eduardo A. Undurraga,Chigozie Jesse Uneke,Rachel L Updike,Olalekan A. Uthman,Benjamin S Chudi Uzochukwu,Job F M van Boven,Santosh Varughese,Tommi Vasankari,S Venkatesh,Narayanaswamy Venketasubramanian,Ramesh Vidavalur,Francesco Saverio Violante,Sergey K Vladimirov,Vasiliy Victorovich Vlassov,Stein Emil Vollset,Fiseha Wadilo,Tolassa Wakayo,Tolassa Wakayo,Yuan-Pang Wang,Marcia R. Weaver,Scott Weichenthal,Elisabete Weiderpass,Robert G. Weintraub,Andrea Werdecker,Ronny Westerman,Harvey Whiteford,Harvey Whiteford,Tissa Wijeratne,Charles Shey Wiysonge,Charles D.A. Wolfe,Charles D.A. Wolfe,Rachel Woodbrook,Anthony D. Woolf,Abdulhalik Workicho,Denis Xavier,Gelin Xu,Simon Yadgir,Mohsen Yaghoubi,Bereket Yakob,Lijing L Yan,Yuichiro Yano,Pengpeng Ye,Hassen Hamid Yimam,Paul S. F. Yip,Naohiro Yonemoto,Seok Jun Yoon,Marcel Yotebieng,Mustafa Z. Younis,Mustafa Z. Younis,Zoubida Zaidi,Maysaa El Sayed Zaki,Elias Asfaw Zegeye,Zerihun Menlkalew Zenebe,Xueying Zhang,Maigeng Zhou,Ben Zipkin,Sanjay Zodpey,Liesl Zühlke,Christopher J L Murray +778 more