J
John Q. Trojanowski
Researcher at University of Pennsylvania
Publications - 1538
Citations - 245534
John Q. Trojanowski is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Alzheimer's disease. The author has an hindex of 226, co-authored 1467 publications receiving 213948 citations. Previous affiliations of John Q. Trojanowski include Vanderbilt University & University of California, San Francisco.
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Journal Article
Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.
Xuanmin He,Carol J. Wikstrand,Henry S. Friedman,S. H. Bigner,Samuel J. Pleasure,John Q. Trojanowski,Darell D. Bigner +6 more
TL;DR: The detection of neurofilament proteins and synaptophysin and the absence of glial fibrillary acidic protein provide strong evidence for a neuronal phenotype of D384 Med, D425 Med, and D458 Med.
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Update on hypothetical model of Alzheimer's disease biomarkers
Clifford R. Jack,David S. Knopman,William J. Jagust,Ronald C. Petersen,Michael W. Weiner,Paul S. Aisen,Leslie M. Shaw,Prashanthi Vemuri,Heather J. Wiste,Stephen D. Weigand,Timothy G. Lesnick,Vernon S. Pankratz,Michael C. Donohue,John Q. Trojanowski +13 more
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Effects of α-tocopherol on an animal model of tauopathies
Hanae Nakashima,Takeshi Ishihara,Osamu Yokota,Seishi Terada,John Q. Trojanowski,Virginia M.-Y. Lee,Shigetoshi Kuroda +6 more
TL;DR: It is suggested that oxidative damage is involved in the pathological mechanisms of the tau Tg mice and that treatment with antioxidative agents like α-tocopherol may prevent neurodegenerative tauopathies.
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Localization of the mitogen activated protein kinase ERK2 in Alzheimer's disease neurofibrillary tangles and senile plaque neurites
TL;DR: It is shown here that a monoclonal antibody to MAP kinases recognizes ERK2 in normal and AD cortex, but ERK1 levels are slightly reduced in the AD brain.
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Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases.
Gabor G. Kovacs,John L. Robinson,Sharon X. Xie,Edward B. Lee,Murray Grossman,David A. Wolk,David J. Irwin,Dan Weintraub,Christopher F. Kim,Theresa Schuck,Ahmed Yousef,Stephanie T. Wagner,EunRan Suh,Vivianna M. Van Deerlin,Virginia M.-Y. Lee,John Q. Trojanowski +15 more
TL;DR: It is found that the amygdala is a hotspot for all ARTAG types, and a conceptual link between primary FTLD-tauopathy and ARTAG-related astrocytic tau pathologies is proposed.