J
John Q. Trojanowski
Researcher at University of Pennsylvania
Publications - 1538
Citations - 245534
John Q. Trojanowski is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Alzheimer's disease. The author has an hindex of 226, co-authored 1467 publications receiving 213948 citations. Previous affiliations of John Q. Trojanowski include Vanderbilt University & University of California, San Francisco.
Papers
More filters
Journal Article
Molecular features of hypothalamic plaques in Alzheimer's disease.
TL;DR: There are substantial molecular and cellular differences in the pathologic features of AD in the hypothalamus compared with those observed in hippocampal and cortical structures, which may provide insight into the pathogenetic mechanisms of AD.
Journal ArticleDOI
Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease
Andrew P. Lieberman,John Q. Trojanowski,Virginia M.-Y. Lee,Brian J. Balin,Xin Shen Ding,Joel H. Greenberg,Donald F. Morrison,Martin Reivich,Murray Grossman +8 more
TL;DR: The hypothesis that a distinct variety of hyperphosphorylated tau in Pick's disease compromises the long‐term viability of selectively vulnerable populations of neurons in frontal cortices that contribute to sentence processing is supported.
Journal ArticleDOI
Human tau pathology transmits glial tau aggregates in the absence of neuronal tau.
Sneha Narasimhan,Lakshmi Changolkar,Dawn M. Riddle,Alexandra Kats,Anna Stieber,Sarah A Weitzman,Bin Zhang,Zhiyong Li,Erik D. Roberson,John Q. Trojanowski,Virginia M.-Y. Lee +10 more
TL;DR: This study shows glial tau pathology can propagate in the absence of neuronal tau, and in particular, oligodendrocytes transmit t Tau pathology via their own processes, independent of neurons.
Journal Article
A detailed immunohistochemical analysis of cerebellar hemangioblastoma: an undifferentiated mesenchymal tumor.
TL;DR: The stromal cell of capillary hemangioblastoma is neither endothelial, neural, epithelial, pericytic, nor neuroendocrine in origin, and is instead of undifferentiated mesenchymal origin.
Journal Article
The neuroendocrine and neural profiles of neuroblastomas, ganglioneuroblastomas, and ganglioneuromas.
Willemina M. Molenaar,David L. Baker,David E Pleasure,Virginia M.-Y. Lee,John Q. Trojanowski +4 more
TL;DR: The above-outlined neuronal profile of peripheral neuroblastic tumors, including NBs, distinguishes this group of tumors from the much-less neuronally differentiated primitive neuroectodermal tumors of the central nervous system.