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Rakesh K. Jain

Researcher at Harvard University

Publications -  1528
Citations -  198912

Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.

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A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

TL;DR: Experiments in mice with a constitutively active PEGylated fluorescent imaging probe support a model where tumor-selective probe distribution is a determinant of increased fluorescence in cancer, and suggest that the tumor specificity of protease-activated imaging probes, such as LUM015, is dependent on both biodistribution and enzyme activity.
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Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: 31P and 1H magnetic resonance spectroscopic studies.

TL;DR: In vivo 31P magnetic resonance spectroscopy after 2 weeks of treatment showed an increase in [phosphocreatine (PCr)+phosphocyclocreatines (PcyCr)]/nucleoside triphosphate (NTP) with increasing concentrations of dietary Cr and cyCr, without changes in absolute NTP contents, indicating that both substrates were equally potent in tumour growth inhibition.
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Rhodococcus imtechensis sp. nov., a nitrophenol-degrading actinomycete

TL;DR: The low levels of DNA-DNA relatedness with the above micro-organisms, and the differences in the biochemical and physiological properties, suggest that strain RKJ300(T) should be classified within a novel species of the genus Rhodococcus, for which the name Rhoditis imtechensis sp.
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Gluconic acid production under varying fermentation conditions by Aspergillus niger

TL;DR: The production of gluconic acid with respect to varying substrate concentrations in submerged (SmF), semisolid-state (SmSF), surface (SF), and solid-state surface (SSF) fermentations was analyzed and it was observed that the SmF and SmSF processes were completed within 6 days of incubation whereas the highest yield was observed after 12 days of fermentation and continued thereafter in the SSF process.