Rakesh K. Jain

TL;DR: In this article, the external quantum efficiency of AlGaN deep ultraviolet (DUV) light-emitting diodes (LEDs) on sapphire substrates is analyzed.

TL;DR: It is reported that targeting angiotensin signaling with losartan can reduce extracellular matrix in ovarian tumors and the associated physical barriers that normally hinder drug delivery and efficacy, leading to better anticancer therapeutic effect.

TL;DR: The researchers found that VEGF inhibition increased the stiffness of colorectal cancer liver metastases, making them more difficult to treat with chemotherapy, and suggested that extracellular matrix components such as HA could be a potential therapeutic target for reducing physical barriers to systemic treatments in patients with mCRC who receive anti-VEGF therapy.

TL;DR: Mechanistic insights into antitumor vascular effects of PDT are provided and novel strategies for tumor treatment with PDT are suggested and suggested.

TL;DR: It is shown that Olig2+ oligodendrocyte precursor-like glioma cells invade by single-cell vessel co-option and preserve the blood-brain barrier (BBB), and glial-encoded pathways regulate distinct gliomas-vascular microenvironmental interactions.