R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Journal ArticleDOI
An Indirect Way to Tame Cancer
TL;DR: The article focuses on research led by the author on how the matrix structure of cancerous tumors squeezes blood vessels, preventing the effectiveness of drug treatments, and the use of angiotensin-blocking drugs to counteract this as of February 2014.
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Interaction of activated natural killer cells with normal and tumor vessels in cranial Windows in mice
TL;DR: It is indicated that A-NK cells bind in high numbers to segments of the vessels of mammary tumors growing in an intracranial site when administered through an arterial route; however, some tumor vessels may escape recognition by these cells.
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Development of sunitinib in hepatocellular carcinoma: rationale, early clinical experience, and correlative studies.
TL;DR: The current progress and future directions for the development of sunitinib in advanced HCC are reviewed.
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Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma.
Eudocia Q. Lee,Dan G. Duda,Alona Muzikansky,Elizabeth R. Gerstner,John G. Kuhn,David A. Reardon,David A. Reardon,Lakshmi Nayak,Lakshmi Nayak,Andrew D. Norden,Andrew D. Norden,Lisa Doherty,Debra LaFrankie,Jennifer Stefanik,Trupti Vardam,Katrina H. Smith,Christine McCluskey,Sarah C. Gaffey,Tracy T. Batchelor,Rakesh K. Jain,Patrick Y. Wen,Patrick Y. Wen +21 more
TL;DR: Plerixafor + bevacizumab was well tolerated in HGG patients and progression-free survival correlated with pretreatment plasma soluble mesenchymal–epithelial transition receptor and sVEGFR1, and overall survival with the change during treatment in CD34+ progenitor/stem cells and CD8 T cells.
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The Bikini Area and Bikini Line as a Location for Anterior Subcutaneous Pelvic Fixation: An Anatomic and Clinical Investigation
TL;DR: Patients are comfortable, mobile and complications are minimized by this procedure, and a rod placed on the Bikini Line which connects screws inserted into the anterior inferior iliac spine on each side does not interfere with sitting, standing, or the neurovascular structures.