R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Journal ArticleDOI
Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy
Fotios Mpekris,Chrysovalantis Voutouri,Myrofora Panagi,James W. Baish,Rakesh K. Jain,Triantafyllos Stylianopoulos +5 more
TL;DR: In this paper , the authors employed a mathematical framework to show that pre-treatment with a normalizing dose of Doxil can improve the efficacy of immune checkpoint inhibition, and showed that the approved nanomedicine Dioxil can induce normalization in a dose-dependent manner by improving tumor perfusion as a result of tissue softening.
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3-Azido-3-deoxy-glycopyranoside derivatives as scaffolds for the synthesis of carbohydrate-based universal pharmacophore mapping libraries.
Rakesh K. Jain,Muthoni G. Kamau,Chunguang Wang,Robert Ippolito,Huiming Wang,Richard G. Dulina,Jan A. Anderson,David Gange,Michael J. Sofia +8 more
TL;DR: The regiospecific syntheses of six monosaccharide scaffolds, 1-6, containing a carboxylic acid, an azido and a free hydroxyl group were accomplished through the utilization of a key intermediate, namely, methyl 3-azido-3-deoxy-beta-D-glucopyranoside.
Journal Article
Degradation of p-hydroxybenzoate via protocatechuate in Arthrobacter protophormiae RKJ100 and Burkholderia cepacia RKJ200
TL;DR: Two bacterial strains isolated from pesticide-contaminated agricultural fields and identified as Arthrobacter protophormiae and Burkholderia cepacia were found to be capable of utilizing p-hydroxybenzoate (PHB) as a sole source of carbon and energy.
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Sclerosing polycystic adenosis of parotid gland: a cytological diagnostic dilemma
TL;DR: A case of SPCA is reported in a male patient with aspiration cytology findings, which is a pseudo-neoplastic lesion of the major salivary glands with histological similarity to fibrocystic disease of the breast.
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Direct, ESR observation of the localized biradical 1,3-dimethyl-1,3-cyclobutadiyl
TL;DR: Observation directe de l'etat triplet du compose cite dans le titre par spectroscopie RPE et etude de ses comportements thermiques as discussed by the authors.