R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
Papers
More filters
Journal Article
Spatial heterogeneity in tumor perfusion measured with functional computed tomography at 0.05 microliter resolution.
TL;DR: High speed functional computed tomography was used to demonstrate tumor vascular heterogenelty and demonstrated that tumor physiology was influenced by cell line and not by location, permitting more detailed prognosis and management.
Journal ArticleDOI
Non-Uniform Plasma Leakage Affects Local Hematocrit and Blood Flow: Implications for Inflammation and Tumor Perfusion
TL;DR: To analyze the interplay among plasma leakage, blood viscosity, and vessel geometry, a mathematical model is developed that explicitly includes blood cells, vessel branching, and focal leakage and suggests that normalization of tumor vessels by anti-angiogenic therapy may improve tumor perfusion via the first two mechanisms.
Journal ArticleDOI
Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells.
TL;DR: A mathematical model was utilized to predict the time course of the development of oxygen and glucose concentration gradients within the tissue-mimetic culture system, and the model and the TMCS provide useful tools for investigating the effect of the metabolic microenvironment on cells in culture.
Journal ArticleDOI
Microcirculatory flow changes during tissue growth.
Thomas E. Dudar,Rakesh K. Jain +1 more
TL;DR: Red blood cell velocities, lumen diameters, and volumetric flow rates were determined as functions of position and time in the microvessels of repairing tissue grown in a transparent rabbit ear chamber to provide a quantitative understanding of the mechanisms underlying neovascularization, tissue growth, and blood flow regulation.
Journal ArticleDOI
Applications of Next Generation High Throughput Sequencing Technologies in Characterization, Discovery and Molecular Interaction of Plant Viruses
TL;DR: An overview of the applications of next generation sequencing technology in characterization, discovery and molecular interaction of plant viruses is provided.