R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Compatibility and the genesis of residual stress by volumetric growth.
TL;DR: The equations of compatibility which are pertinant for growth strain fields are collected and examples are given in simply-connected and multiply-connected regions.
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Cell-surface sensors for real-time probing of cellular environments
Weian Zhao,Sebastian Schafer,Jonghoon Choi,Yvonne J. Yamanaka,Maria L. Lombardi,Suman Bose,Alicia L. Carlson,Joseph A. Phillips,Weisuong Teo,Ilia A. Droujinine,Cheryl H. Cui,Rakesh K. Jain,Jan Lammerding,J. Christopher Love,Charles P. Lin,Debanjan Sarkar,Rohit Karnik,Jeffrey M. Karp +17 more
TL;DR: In this paper, an aptamer (a short length of single-stranded DNA) is attached to platelet-derived growth factor (PDGF) and contains a pair of fluorescent dyes.
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Vasculogenic mimicry: how convincing, how novel, and how significant?
TL;DR: The evidence presented in Maniotis et al for a functionally significant contribution of tumor cell-lined blood vessels to vascularization and blood flow in uveal melanomas is neither persuasive nor novel.
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Glioblastoma Recurrence after Cediranib Therapy in Patients: Lack of “Rebound” Revascularization as Mode of Escape
Emmanuelle di Tomaso,Matija Snuderl,Walid S. Kamoun,Dan G. Duda,Pavan K. Auluck,Ladan Fazlollahi,Ovidiu C. Andronesi,Matthew P. Frosch,Patrick Y. Wen,Scott R. Plotkin,E. Tessa Hedley-Whyte,A. Gregory Sorensen,Tracy T. Batchelor,Rakesh K. Jain +13 more
TL;DR: It is shown that rGBMs switch their growth pattern after anti-VEGF therapy--characterized by lower tumor cellularity in the central area, decreased pseudopalisading necrosis, and blood vessels with normal molecular expression and morphology--without a second wave of angiogenesis.
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Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks
Walid S. Kamoun,Sung-Suk Chae,Delphine A. Lacorre,James A. Tyrrell,Mariela Mitre,Marijn A. Gillissen,Dai Fukumura,Rakesh K. Jain,Lance L. Munn +8 more
TL;DR: This work developed methodologies for simultaneously quantifying blood flow (velocity, flux, hematocrit and shear rate) in extended networks at single-capillary resolution in vivo and shows that blood velocity profiles are asymmetric near intussusceptive tissue structures in tumors in mice.