R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
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Journal ArticleDOI
Antibody-Directed Effector Cell Therapy of Tumors: Analysis and Optimization Using a Physiologically Based Pharmacokinetic Model
Stuart W. Friedrich,Stephany C. Linz,Brian R. Stoll,Laurence T. Baxter,Lance L. Munn,Rakesh K. Jain +5 more
TL;DR: The results suggest that the design of the BFA is critical and the binding constants of the antigen and lymphocyte binding epitopes need to be optimized for successful therapy.
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Quantifying solid stress and elastic energy from excised or in situ tumors.
Hadi Tavakoli Nia,Meenal Datta,Meenal Datta,Giorgio Seano,Peigen Huang,Lance L. Munn,Rakesh K. Jain +6 more
TL;DR: Three new techniques to rigorously measure and map solid stress in both human and murine tumors that are able to account for heterogeneity in the tumor microenvironment are developed and preserved for subsequent histological analyses in matched tumor sections.
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p-Nitrophenol Degradation via 4-Nitrocatechol in Burkholderia sp. SJ98 and Cloning of Some of the Lower Pathway Genes
Archana Chauhan,Gunjan Pandey,Narinder K. Sharma,Debarati Paul,Janmejay Pandey,Rakesh K. Jain +5 more
TL;DR: This is one of the first conclusive reports for 4-NC and BT mediated degradation of PNP in a Gram negative organism.
Journal Article
Primary Tumor Size-dependent Inhibition of Angiogenesis at a Secondary Site: An Intravital Microscopic Study in Mice
TL;DR: The relationship between the size of a primary tumor and its ability to inhibit angiogenesis at a secondary site and the effects of the primary tumor on physiological properties of newly formed vessels at the secondary site are evaluated.
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Desulphurization of dibenzothiophene and diesel oils by bacteria.
TL;DR: To study the desulphurization of dibenzothiophene by two bacteria isolated from oil‐contaminated soil/sludge in order to use them for reducing the sulphur content of diesel oil in compliance with environmental regulations.