R
Rakesh K. Jain
Researcher at Harvard University
Publications - 1528
Citations - 198912
Rakesh K. Jain is an academic researcher from Harvard University. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 200, co-authored 1467 publications receiving 177727 citations. Previous affiliations of Rakesh K. Jain include Government Medical College, Thiruvananthapuram & University of Oslo.
Papers
More filters
Journal ArticleDOI
Diffusion and partitioning of proteins in charged agarose gels.
TL;DR: For diffusion of globular proteins through gel membranes of like charge, electrostatic effects on the effective diffusivity (Deff = phi D) are likely to result primarily from variations in phi with only small contributions from the intramembrane Diffusivity.
Journal ArticleDOI
Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy.
Kyrre E. Emblem,Kim Mouridsen,Kim Mouridsen,Atle Bjørnerud,Atle Bjørnerud,Christian T. Farrar,Dominique Jennings,Ronald Borra,Ronald Borra,Patrick Y. Wen,Percy Ivy,Tracy T. Batchelor,Bruce R. Rosen,Rakesh K. Jain,A. Gregory Sorensen,A. Gregory Sorensen +15 more
TL;DR: It is demonstrated using VAI that anti-angiogenic therapy can improve microcirculation and oxygen saturation and reduce vessel calibers in patients with recurrent glioblastomas and, more crucially, that patients with these responses have prolonged survival.
p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
David G. Kirsch,Philip M. Santiago,Emmanuelle di Tomaso,Julie M. Sullivan,Wu-Shiun Hou,Talya L. Dayton,Laura B. Jeffords,Pooja Sodha,Kim L. Mercer,Rhianna Cohen,Osamu Takeuchi,Stanley J. Korsmeyer,Roderick T. Bronson,Carla F. Kim,Kevin M. Haigis,Rakesh K. Jain,Tyler Jacks,Tyler Jacks +17 more
TL;DR: It is suggested that the GI syndrome is caused by the death of GI epithelium cells and that these epithelial cells die by a mechanism that is regulated by p53 but independent of apoptosis.
Journal ArticleDOI
Degradation of phenanthrene by different bacteria: evidence for novel transformation sequences involving the formation of 1-naphthol
TL;DR: Four polycyclic aromatic hydrocarbon- degrading bacteria, namely Arthrobacter sulphureus RKJ4, Acidovorax delafieldii P4-1, Brevibacterium sp.
Journal ArticleDOI
Engineering and physical sciences in oncology: challenges and opportunities
TL;DR: The research advances, opportunities and challenges for integrating engineering and physical sciences with oncology to develop new methods to study, detect and treat cancer are reviewed, and the future outlook for these emerging areas is described.