Institution
National Cheng Kung University
Education•Tainan City, Taiwan•
About: National Cheng Kung University is a education organization based out in Tainan City, Taiwan. It is known for research contribution in the topics: Population & Thin film. The organization has 49723 authors who have published 69799 publications receiving 1437420 citations. The organization is also known as: NCKU.
Topics: Population, Thin film, Microstructure, Dielectric, Heat transfer
Papers published on a yearly basis
Papers
More filters
••
University of Oxford1, Broad Institute2, Swiss Federal Institute of Aquatic Science and Technology3, University of Bern4, Wellcome Trust/Cancer Research UK Gurdon Institute5, Wellcome Trust Sanger Institute6, University of Konstanz7, Agency for Science, Technology and Research8, Reed College9, Stanford University10, California Institute of Technology11, Benaroya Research Institute12, University of Rennes13, Georgia Institute of Technology14, University of Maryland, College Park15, University of Basel16, University of Texas at Austin17, Tokyo Institute of Technology18, National Museum of Natural History19, University of Stirling20, Carnegie Institution for Science21, National Cheng Kung University22, Science for Life Laboratory23, Norwich University24
TL;DR: This article found an excess of gene duplications in the East African lineage compared to Nile tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs.
Abstract: Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we sequenced the genomes and transcriptomes of five lineages of African cichlids: the Nile tilapia (Oreochromis niloticus), an ancestral lineage with low diversity; and four members of the East African lineage: Neolamprologus brichardi/pulcher (older radiation, Lake Tanganyika), Metriaclima zebra (recent radiation, Lake Malawi), Pundamilia nyererei (very recent radiation, Lake Victoria), and Astatotilapia burtoni (riverine species around Lake Tanganyika). We found an excess of gene duplications in the East African lineage compared to tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs. In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome-wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms. We conclude that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification.
832 citations
••
Washington University in St. Louis1, Taipei Veterans General Hospital2, St John of God Subiaco Hospital3, National Cheng Kung University4, Translational Genomics Research Institute5, Hebron University6, Seoul National University Hospital7, The Royal Marsden NHS Foundation Trust8, China Medical University (Taiwan)9, National Health Research Institutes10
TL;DR: Nanoliposomal irinotecan in combination with fluorouracil and folinic acid extends survival with a manageable safety profile in patients with metastatic pancreatic ductal adenocarcinoma who previously received gemcitabine-based therapy.
830 citations
••
TL;DR: The independence assumptions in cross validation are introduced, and the circumstances that satisfy the assumptions are also addressed, which are used to derive the sampling distributions of the point estimators for k-fold and leave-one-out cross validation.
798 citations
••
TL;DR: Comparisons show that GRA is efficient for solving MADM problem, which involves picking the best from among multiple available alternatives for all performance attributes.
797 citations
••
TL;DR: This article offers a tutorial on several prevalent methods to enhance security at the physical layer in wireless networks based on their characteristic features into five categories, each of which is discussed in terms of two metrics.
Abstract: Wireless networking plays an extremely important role in civil and military applications. However, security of information transfer via wireless networks remains a challenging issue. It is critical to ensure that confidential data are accessible only to the intended users rather than intruders. Jamming and eavesdropping are two primary attacks at the physical layer of a wireless network. This article offers a tutorial on several prevalent methods to enhance security at the physical layer in wireless networks. We classify these methods based on their characteristic features into five categories, each of which is discussed in terms of two metrics. First, we compare their secret channel capacities, and then we show their computational complexities in exhaustive key search. Finally, we illustrate their security requirements via some examples with respect to these two metrics.
770 citations
Authors
Showing all 49872 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
Yang Yang | 164 | 2704 | 144071 |
R. E. Hughes | 154 | 1312 | 110970 |
Mercouri G. Kanatzidis | 152 | 1854 | 113022 |
Thomas J. Smith | 140 | 1775 | 113919 |
Hui Li | 135 | 2982 | 105903 |
Gerald M. Reaven | 133 | 799 | 80351 |
Chi-Huey Wong | 129 | 1220 | 66349 |
Joseph P. Vacanti | 119 | 441 | 50739 |
Kai Nan An | 109 | 953 | 51638 |
Ding-Shinn Chen | 104 | 774 | 46068 |
James D. Neaton | 101 | 331 | 64719 |
David C. Christiani | 100 | 1052 | 55399 |
Jo Shu Chang | 99 | 639 | 37487 |
Yu Shyr | 98 | 542 | 39527 |