Junction Adhesion Molecule Is a Receptor for Reovirus
Erik S. Barton,J. Craig Forrest,Jodi L. Connolly,James D. Chappell,Yuan Liu,Frederick J. Schnell,Asma Nusrat,Charles A. Parkos,Terence S. Dermody +8 more
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TLDR
Reovirus interaction with cell-surface receptors is a critical determinant of both cell-type specific tropism and virus-induced intracellular signaling events that culminate in cell death.About:
This article is published in Cell.The article was published on 2001-02-09 and is currently open access. It has received 627 citations till now. The article focuses on the topics: Tropism & Junctional Adhesion Molecule A.read more
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Distantly related hepaciviruses share common entry factor, Claudin-1
Kamilla Toon,Mphatso D Kalemera,Machaela Palor,Nicola J. Rose,Y. Takeuchi,Joe Grove,Giada Mattiuzzo +6 more
TL;DR: Pseudotyped viruses are developed to elucidate the entry factors of GB virus-B (GBV-B), the first hepacivirus described in an animal, closely related to hepatitis C virus (HCV), and identified a protein, Claudin-1, which facilitates the entry of HCV-related he pacivirus, but with a mechanism not described for HCV.
Journal ArticleDOI
GB Virus B and Hepatitis C Virus, Distantly Related Hepaciviruses, Share an Entry Factor, Claudin-1
Kamilla Toon,Mphatso D Kalemera,Machaela Palor,Nicola J. Rose,Y. Takeuchi,Joe Grove,Giada Mattiuzzo +6 more
TL;DR: In this article , pseudotyped GB virus B (GBV-B) was used to elucidate the entry factors of GB virus and showed that claudin-1 is essential for GBV-b infection, indicating the GBV and HCV share an entry factor.
Dissertation
Pathogen host interactions: proteomics of Influenza NEP during infection reveals an antagonistic role in the formation of tight junctions
TL;DR: This work discovered new host factors interacting with the influenza nuclear export protein (NEP) using an engineered influenza virus expressing NEP with an N-terminal 3xFLAG tag and revealed a new role for NEP as a tight junction antagonist.
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TL;DR: Immunological synapse formation is now shown to be an active and dynamic mechanism that allows T cells to distinguish potential antigenic ligands and was a determinative event for T cell proliferation.
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